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. 2023 Jul 11;9(7):e18140.
doi: 10.1016/j.heliyon.2023.e18140. eCollection 2023 Jul.

Origin, dietary exposure, and toxicity of endocrine-disrupting food chemical contaminants: A comprehensive review

Leila Peivasteh-Roudsari  1 , Raziyeh Barzegar-Bafrouei  2 , Kurush Aghbolagh Sharifi  3 , Shamimeh Azimisalim  4 , Marziyeh Karami  5 , Solmaz Abedinzadeh  6 , Shabnam Asadinezhad  7 , Behrouz Tajdar-Oranj  1 , Vahideh Mahdavi  8 , Adel Mirza Alizadeh  9   10 , Parisa Sadighara  5 , Margherita Ferrante  11 , Gea Oliveri Conti  11 , Aynura Aliyeva  12 , Amin Mousavi Khaneghah  12   13
Affiliations

Origin, dietary exposure, and toxicity of endocrine-disrupting food chemical contaminants: A comprehensive review

Leila Peivasteh-Roudsari et al. Heliyon. .

Abstract

Endocrine-disrupting chemicals (EDCs) are a growing public health concern worldwide. Consumption of foodstuffs is currently thought to be one of the principal exposure routes to EDCs. However, alternative ways of human exposure are through inhalation of chemicals and dermal contact. These compounds in food products such as canned food, bottled water, dairy products, fish, meat, egg, and vegetables are a ubiquitous concern to the general population. Therefore, understanding EDCs' properties, such as origin, exposure, toxicological impact, and legal aspects are vital to control their release to the environment and food. The present paper provides an overview of the EDCs and their possible disrupting impact on the endocrine system and other organs.

Keywords: Dietary exposure; Endocrine disruption; Food safety; Public health.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

Figures

Fig. 1
Fig. 1
EDCs-mediated activation of AHR and oxidative stress.
Fig. 2
Fig. 2
Chemical structures of the main EDCs.
Fig. 3
Fig. 3
A Food web bioaccumulation of phthalates through marine system [].
See this image and copyright information in PMC

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