doi: 10.1128/JVI.58.1.220-222.1986.
Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis
- PMID: 3754016
- PMCID: PMC252897
- DOI: 10.1128/JVI.58.1.220-222.1986
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Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis
J Virol.
1986 Apr.
Abstract
A monoclonal antibody against the fusion (F) protein of mumps virus was found to confer marked protection in mumps virus-induced encephalitis. Almost total prevention of extensive brain necrosis was found. This study indicates that the virus F protein is directly involved in the pathogenesis of brain necrosis.
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