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. 1986 Apr;58(1):220-2.
doi: 10.1128/JVI.58.1.220-222.1986.

Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis

A Löve, R Rydbeck, G Utter, C Orvell, K Kristensson, E Norrby

Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis

A Löve et al. J Virol. 1986 Apr.

Abstract

A monoclonal antibody against the fusion (F) protein of mumps virus was found to confer marked protection in mumps virus-induced encephalitis. Almost total prevention of extensive brain necrosis was found. This study indicates that the virus F protein is directly involved in the pathogenesis of brain necrosis.

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