Dawn of development: Exploring early human embryogenesis using stem cells
- PMID: 37541206
- DOI: 10.1016/j.stem.2023.07.009
Dawn of development: Exploring early human embryogenesis using stem cells
Abstract
Exploring the early stages of human embryonic development poses significant difficulties owing to ethical and technical limitations. Two recent studies in Nature report the self-organization of human stem cells into 3D embryoids that model features of the early post-implantation stages of human development.1,2.
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Pluripotent stem cell-derived model of the post-implantation human embryo.Nature. 2023 Oct;622(7983):584-593. doi: 10.1038/s41586-023-06368-y. Epub 2023 Jun 27. Nature. 2023. PMID: 37369347 Free PMC article.
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Self-patterning of human stem cells into post-implantation lineages.Nature. 2023 Oct;622(7983):574-583. doi: 10.1038/s41586-023-06354-4. Epub 2023 Jun 27. Nature. 2023. PMID: 37369348 Free PMC article.
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