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Comment
. 2023 Aug 4;8(1):295.
doi: 10.1038/s41392-023-01568-4.

Commanding the Commander: structure of a key protein machinery in endosomal trafficking

Xin Yong  1 , Chunzhuang Zhou  1 , Daniel D Billadeau  2 , Da Jia  3
Affiliations
Comment

Commanding the Commander: structure of a key protein machinery in endosomal trafficking

Xin Yong et al. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
a The structure model of the Commander complex (Model Archive: ma-ri7tb), adapted from graphic abstract of the Cell study. b The structural models of the SNX3-Retromer (PDB:7BLP) and SNX-BAR-Retromer complex (PDB:6H7W) on the membrane. c Comparison of Retriever and Retromer
See this image and copyright information in PMC

Comment on

  • Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
    Healy MD, McNally KE, Butkovič R, Chilton M, Kato K, Sacharz J, McConville C, Moody ERR, Shaw S, Planelles-Herrero VJ, Yadav SKN, Ross J, Borucu U, Palmer CS, Chen KE, Croll TI, Hall RJ, Caruana NJ, Ghai R, Nguyen THD, Heesom KJ, Saitoh S, Berger I, Schaffitzel C, Williams TA, Stroud DA, Derivery E, Collins BM, Cullen PJ. Healy MD, et al. Cell. 2023 May 11;186(10):2219-2237.e29. doi: 10.1016/j.cell.2023.04.003. Cell. 2023. PMID: 37172566 Free PMC article.

References

    1. Healy MD, et al. Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome. Cell. 2023;186:2219–2237.e2229. doi: 10.1016/j.cell.2023.04.003. - DOI - PMC - PubMed
    1. Laulumaa, S., Kumpula, E., Huiskonen, J. T. & Varjosalo, M. Structure and Interactions of the Endogenous Human Commander Complex. Preprint at 10.1101/2023.04.03.535349 (2023). - PMC - PubMed
    1. Boesch, D. J. et al. Structural Organization of the Retriever-CCC Endosomal Recycling Complex. Preprint at 10.1101/2023.06.06.543888 (2023). - PMC - PubMed
    1. McNally KE, et al. Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling. Nat. Cell Biol. 2017;19:1214–1225. doi: 10.1038/ncb3610. - DOI - PMC - PubMed
    1. Yong X, et al. SNX27-FERM-SNX1 complex structure rationalizes divergent trafficking pathways by SNX17 and SNX27. Proc. Natl Acad. Sci. USA. 2021;118:e2105510118. doi: 10.1073/pnas.2105510118. - DOI - PMC - PubMed

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