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. 2023 Mar;23(1):72-82.
doi: 10.4314/ahs.v23i1.9.

Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria

Olukemi Adekanmbi  1   2 , Olayinka Ilesanmi  3   4 , Olusola Idowu  5   6 , Arinola Esan  2 , Yemi R Raji  1   2 , Adeola Fowotade  7 , Olubunmi Ogunlade  2 , Adegboyega Akere  1   2 , Oluwaseun Ololade  2 , Kehinde Ojifinni  8 , Olurotimi Akinola  8 , Akintunde Orunmuyi  9 , Uwom Eze  10 , Victor Akinmoladun  11   12 , Abiodun Adeoye  2   13 , Akindele Adebiyi  3   4 , E Oluwabunmi Olapade-Olaopa  14   15 , Jesse A Otegbayo  1   2 , Kayode Osungbade  16   17
Affiliations

Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria

Olukemi Adekanmbi et al. Afr Health Sci. 2023 Mar.

Abstract

Background: Data regarding the features and outcomes of hospitalized COVID-19 patients in Africa are increasingly available.

Objectives: To describe socio-demographic, clinical and laboratory characteristics and outcomes of COVID-19 patients.

Methods: A cross-sectional study of 86 adult patients hospitalized with COVID-19 between March and November 2020. Characteristics were described in survivors and non-survivors.

Results: Mean age was 60.9±16.1 years, 53(61.6%) were male. Co-morbidities were found in 77(89.5%) patients. On severity, 6(7%) were mild, 23(26.7%) moderate, 51(59.3%) severe and 6(7%) critical. Oxygen saturation and respiratory rate were 71±22% and 38±11/minute in non-survivors and 90±7% and 31±7/minute in survivors respectively (p<0.001, p<0.001)). Overall mortality was 47.7% with no death among patients with mild disease and deaths in all patients with critical disease. Duration of hospitalization was 2.0(1.0-4.5) days in those who died and 12(7.0-15.0) days in those who survived (p<0.001). Of the 42 patients that received dexamethasone, 11(26.2%) died, while 31(73.8%) survived (p=<0.001).

Conclusion: Most of the patients had co-morbidities and there was high mortality in patients with severe and critical COVID-19. Mean oxygen saturation was low and respiratory rate high overall. Factors associated with mortality included: Significantly greater hypoxia and tachypnea, less dexamethasone use and shorter hospitalization.

Keywords: COVID-19; COVID-19 mortality; SARS CoV-2.

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Conflict of interest statement

The authors declare that there are no relationships or support which might be perceived as constituting a conflict of interest.

Figures

Figure 1
Figure 1
Mortality by month in 2020 during the first wave of COVID-19 among hospitalized COVID19 patients at the University College Hospital, Ibadan
See this image and copyright information in PMC

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