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Review
. 2023 Jul 27:9:e11.
doi: 10.15420/cfr.2023.05. eCollection 2023.

Global Public Health Burden of Heart Failure: An Updated Review

Bahira Shahim  1   2 , Chris J Kapelios  3 , Gianluigi Savarese  1   2 , Lars H Lund  1   2
Affiliations
Review

Global Public Health Burden of Heart Failure: An Updated Review

Bahira Shahim et al. Card Fail Rev. .

Abstract

Heart failure (HF) is a rapidly growing public health issue with an estimated prevalence of 64 million people globally. Although the incidence of HF has stabilised worldwide and seems to be declining in developed countries, the prevalence is increasing due to the ageing of the population, improved survival after MI and improved treatment and survival of patients with HF. Yet, HF remains associated with high mortality and morbidity, poor quality of life and functional capacity, and confers a substantial burden to the healthcare system. The prevalence, incidence, mortality and morbidity rates reported show geographical variations, depending on the different aetiologies and clinical characteristics observed among patients with HF. In this review, we provide an overview of the global epidemiology of HF with updated data on prevalence, incidence, mortality and morbidity worldwide.

Keywords: Heart failure; epidemiology; heart failure with mildly reduced ejection fraction; heart failure with preserved ejection fraction; heart failure with reduced ejection fraction; incidence; morbidity; mortality; prevalence.

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Conflict of interest statement

Disclosures: GS has received funding from Vifor Pharma, Boehringer Ingelheim, AstraZeneca, Merck, Cytokinetics, Novartis, Boston Scientific, Pharmacosmos, Bayer and Horizon; consulting fees from Teva, MedEd Global Solutions, Genesis Medical, Agence Nationale de la Recherche, Muir Health, Atheneum and Vifor Pharma; honoraria from Servier, Cytokinetics, Medtronic, Dynamicom Education, Vifor Pharma, Roche, TMA Healthcare Ltd, MedEd Global Solutions, AstraZeneca, Novartis; and has participated on advisory boards for AstraZeneca, Uppsala Clinical Research Center, Servier, Edwards and Vifor Pharma. LHL has received grants from AstraZeneca, Vifor Pharma, Boston Scientific, Boehringer Ingelheim, Novartis; consulting fees from Merck, Vifor Pharma, AstraZeneca, Bayer, Pharmacosmos, MSD, Medscape, Sanofi, Lexicon, Myokardia, Boehringer Ingelheim, Servier, Edwards Life Sciences and Alleviant Medical; speaker’s honoraria from Abbott, Orion Pharma, Medscape, Radcliffe, AstraZeneca, Novartis, Boehringer Ingelheim and Bayer; has stock ownership in AnaCardio; is a board member for the European Society of Cardiology Heart Failure Association and the Swedish Society of Cardiology; and is on the Cardiac Failure Review editorial board; this did not influence peer review. All other authors have no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. Prevalence of Heart Failure Worldwide
Figure 2:
Figure 2:. Incidence of Heart Failure Worldwide
Figure 3:
Figure 3:. Summary of Trends in Global Burden of Heart Failure
See this image and copyright information in PMC

References

    1. Khan MS, Shahid I, Fonarow GC, Greene SJ. Classifying heart failure based on ejection fraction: imperfect but enduring. Eur J Heart Fail. 2022;24:1154–7. doi: 10.1002/ejhf.2470. - DOI - PubMed
    1. Lund LH, Pitt B, Metra M. Left ventricular ejection fraction as the primary heart failure phenotyping parameter. Eur J Heart Fail. 2022;24:1158–61. doi: 10.1002/ejhf.2576. - DOI - PubMed
    1. Savarese G, Stolfo D, Sinagra G, Lund LH. Heart failure with mid-range or mildly reduced ejection fraction. Nat Rev Cardiol. 2022;19:100–16. doi: 10.1038/s41569-021-00605-5. - DOI - PMC - PubMed
    1. Bozkurt B, Coats AJS, Tsutsui H et al. Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure: endorsed by the Canadian Heart Failure Society, Heart Failure Association of India, Cardiac Society of Australia and New Zealand, and Chinese Heart Failure Association. Eur J Heart Fail. 2021;23:352–80. doi: 10.1002/ejhf.2115. - DOI - PubMed
    1. York MK, Gupta DK, Reynolds CF et al. B-type natriuretic peptide levels and mortality in patients with and without heart failure. J Am Coll Cardiol. 2018;71:2079–88. doi: 10.1016/j.jacc.2018.02.071. - DOI - PMC - PubMed