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Review
. 2023 Jul 21:36:11564.
doi: 10.3389/ti.2023.11564. eCollection 2023.

European Society of Organ Transplantation (ESOT) Consensus Statement on Prehabilitation for Solid Organ Transplantation Candidates

Coby Annema  1 , Stefan De Smet  2   3   4 , Ellen M Castle  5 , Yasna Overloop  6 , Joost M Klaase  7 , Tania Janaudis-Ferreira  8   9 , Sunita Mathur  10 , Evangelia Kouidi  11 , Maria Jose Perez Saez  12 , Christophe Matthys  6   13 , Fabienne Dobbels  14 , Pisana Ferrari  15 , Justyna Gołębiewska  16 , Anna Mrzljak  17 , Peter Girman  18 , Michael Perch  19   20 , Victor Lopez-Lopez  21 , Colin White  22 , Dmytro Koval  23 , Sharlene Greenwood  24   25 , Diethard Monbaliu  4   26
Affiliations
Review

European Society of Organ Transplantation (ESOT) Consensus Statement on Prehabilitation for Solid Organ Transplantation Candidates

Coby Annema et al. Transpl Int. .

Abstract

There is increasingly growing evidence and awareness that prehabilitation in waitlisted solid organ transplant candidates may benefit clinical transplant outcomes and improve the patient's overall health and quality of life. Lifestyle changes, consisting of physical training, dietary management, and psychosocial interventions, aim to optimize the patient's physical and mental health before undergoing surgery, so as to enhance their ability to overcome procedure-associated stress, reduce complications, and accelerate post-operative recovery. Clinical data are promising but few, and evidence-based recommendations are scarce. To address the need for clinical guidelines, The European Society of Organ Transplantation (ESOT) convened a dedicated Working Group "Prehabilitation in Solid Organ Transplant Candidates," comprising experts in physical exercise, nutrition and psychosocial interventions, to review the literature on prehabilitation in this population, and develop recommendations. These were discussed and voted upon during the Consensus Conference in Prague, 13-15 November 2022. A high degree of consensus existed amongst all stakeholders including transplant recipients and their representatives. Ten recommendations were formulated that are a balanced representation of current published evidence and real-world practice. The findings and recommendations of the Working Group on Prehabilitation for solid organ transplant candidates are presented in this article.

Keywords: exercise; nutrition; prehabilitation; psychosocial interventions; solid organ transplant candidates.

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Conflict of interest statement

DM is a senior researcher of The Research Foundation- Flanders. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Flow chart of study selection process exercise interventions with reasons for exclusion. Note: n = number of studies. Figure adapted from: Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffman TC, Mulrow CD, et al. The PRIMSA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 2021; 372:n71, doi:10.1136/bmj.n71. For more information visit http://www.prisma-statement.org/.
FIGURE 2
FIGURE 2
Flow chart of study selection process nutritional interventions with reasons for exclusion.
FIGURE 3
FIGURE 3
Flow chart of study selection process psychosocial interventions with reasons for exclusion.
FIGURE 4
FIGURE 4
Risk of Bias assessment RCTs exercise intervention studies.
FIGURE 5
FIGURE 5
Risk of Bias assessment RCTs nutritional intervention studies.
FIGURE 6
FIGURE 6
Risk of Bias assessment RCTs psychosocial intervention studies.
See this image and copyright information in PMC

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