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. 1986 May;45(2-3):253-61.
doi: 10.1016/0303-7207(86)90155-3.

Studies on the biosynthesis of ecdysone by the Y-organs of Carcinus maenas

F Lachaise, M F Meister, C Hétru, R Lafont

Studies on the biosynthesis of ecdysone by the Y-organs of Carcinus maenas

F Lachaise et al. Mol Cell Endocrinol. 1986 May.

Abstract

High specific activity tritiated ecdysone precursor, 2,22,25-trideoxyecdysone, was incubated with Y-organs from intermoult and premoult shore crabs. Several metabolites were identified among which ecdysone and 25-deoxyecdysone. The concomitant production of these 2 molecules by Y-organs and their subsequent hydroxylation at C-20 by peripheral tissues, provide an explanation for the presence of both 20-hydroxyecdysone and ponasterone A (25-deoxy-20-hydroxyecdysone) in the circulating haemolymph of crabs.

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