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. 2024;22(10):1720-1732.
doi: 10.2174/1570159X21666230807144750.

Bibliometric Analysis of the Research Status and Global Trends in Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease from 2002 to 2022

Affiliations

Bibliometric Analysis of the Research Status and Global Trends in Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease from 2002 to 2022

Haipeng Cai et al. Curr Neuropharmacol. 2024.

Abstract

Background: Several reviews on behavioral and psychological symptoms (BPSDs) in patients with Alzheimer's disease (AD) have summarized the current state of this field, but global trends are unclear.

Objective: This study utilized CiteSpace to provide a global overview of the current state of research on AD and its BPSDs and to predict future research trends in the field.

Methods: Data were retrieved from the Web of Science Core Collection. Bibliometric and cooccurrence analyses were performed using CiteSpace software. In total, 787 valid publications were included in the analysis.

Results: Publications on AD and BPSD have shown an increasing trend since 2002. The United States and the University of Toronto were the countries and institutions with the highest total number of publications, respectively. Japan and China were the second and third most influential in the field. Clive Ballard was the top author in terms of the number of publications. Journal of Alzheimer's Disease had the highest number of publications on this topic. Co-occurrence analysis showed that AD, behavioral symptoms, cognitive impairment, and early markers are hot topics in this area. Non-drug management of BPSDs, pharmacological treatment, and physiotherapy will be a hot topic in this field in the future.

Conclusion: Our study visualized the relevant articles over the past 21 years to detect global hotspots and trends. Our findings may help researchers to identify research hotspots in this field and will help in the selection of appropriate research topics, while possibly leading to cross-regional cooperation.

Keywords: Alzheimer’s disease; CiteSpace; behavioral and psychological symptoms of dementia; bibliometrics analysis; cognitive impairment.; global trends.

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Conflict of interest statement

The authors declare no conflict of interest, financial or otherwise.

Figures

Fig. (1)
Fig. (1)
Flow chart of the study.
Fig. (2)
Fig. (2)
(A) The global distribution of countries of the research. (B) The number of publications from 2002 to 2022.
Fig. (3)
Fig. (3)
(A) Collaboration among institutions. (B) Collaboration among authors.
Fig. (4)
Fig. (4)
(A) Top 30 keywords with the strongest citation bursts (B) Top 30 references with the strongest citation bursts.

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References

    1. Gulisano W., Maugeri D., Baltrons M.A., Fà M., Amato A., Palmeri A., D’Adamio L., Grassi C., Devanand D.P., Honig L.S., Puzzo D., Arancio O. Role of Amyloid-β and Tau Proteins in Alzheimer’s Disease: Confuting the amyloid cascade. J. Alzheimers Dis. 2018;64(s1):S611–S631. doi: 10.3233/JAD-179935. - DOI - PMC - PubMed
    1. Livingston G., Huntley J., Sommerlad A., Ames D., Ballard C., Banerjee S., Brayne C., Burns A., Cohen-Mansfield J., Cooper C., Costafreda S.G., Dias A., Fox N., Gitlin L.N., Howard R., Kales H.C., Kivimäki M., Larson E.B., Ogunniyi A., Orgeta V., Ritchie K., Rockwood K., Sampson E.L., Samus Q., Schneider L.S., Selbæk G., Teri L., Mukadam N. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet. 2020;396(10248):413–446. doi: 10.1016/S0140-6736(20)30367-6. - DOI - PMC - PubMed
    1. Supporting informal caregivers of people living with dementia. 2017. Available from: http://www.who.int/mental_health/neurology/dementia/dementia_the maticbr....
    1. Querfurth H.W., LaFerla F.M. Alzheimer’s Disease. N. Engl. J. Med. 2010;362(4):329–344. doi: 10.1056/NEJMra0909142. - DOI - PubMed
    1. Scheltens P., Blennow K., Breteler M.M.B., de Strooper B., Frisoni G.B., Salloway S., Van der Flier W.M. Alzheimer’s disease. Lancet. 2016;388(10043):505–517. doi: 10.1016/S0140-6736(15)01124-1. - DOI - PubMed