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Review
. 2023;21(12):2481-2486.
doi: 10.2174/1570159X21666230807150523.

Probiotic Influences on Motor Skills: A Review

Robert Lalonde  1 , Catherine Strazielle  1   2
Affiliations
Review

Probiotic Influences on Motor Skills: A Review

Robert Lalonde et al. Curr Neuropharmacol. 2023.

Abstract

The effects of probiotics have mostly been shown to be favorable on measures of anxiety and stress. More recent experiments indicate single- and multi-strain probiotics in treating motorrelated diseases. Initial studies in patients with Parkinson's disease and Prader-Willi syndrome are concordant with this hypothesis. In addition, probiotics improved motor coordination in normal animals and models of Parkinson's disease, multiple sclerosis, and spinal cord injury as well as grip strength in hepatic encephalopathy. Further studies should delineate the most optimal bacterial profile under each condition.

Keywords: Bifidobacteria; Lactobacilli; Parkinson’s disease; hepatic encephalopathy; motor coordination; multiple sclerosis.

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Conflict of interest statement

The authors declare no conflict of interest, financial or otherwise.

References

    1. Bermúdez-Humarán L.G., Salinas E., Ortiz G.G., Ramirez-Jirano L.J., Morales J.A., Bitzer-Quintero O.K. From probiotics to psychobiotics: live beneficial bacteria which act on the brain-gut axis. Nutrients. 2019;11(4):890. doi: 10.3390/nu11040890. - DOI - PMC - PubMed
    1. Cryan J.F., O’Riordan K.J., Cowan C.S.M., Sandhu K.V., Bastiaanssen T.F.S., Boehme M., Codagnone M.G., Cussotto S., Fulling C., Golubeva A.V., Guzzetta K.E., Jaggar M., Long-Smith C.M., Lyte J.M., Martin J.A., Molinero-Perez A., Moloney G., Morelli E., Morillas E., O’Connor R., Cruz-Pereira J.S., Peterson V.L., Rea K., Ritz N.L., Sherwin E., Spichak S., Teichman E.M., van de Wouw M., Ventura-Silva A.P., Wallace-Fitzsimons S.E., Hyland N., Clarke G., Dinan T.G. The microbiota-gut-brain axis. Physiol. Rev. 2019;99(4):1877–2013. doi: 10.1152/physrev.00018.2018. - DOI - PubMed
    1. Zagórska A., Marcinkowska M., Jamrozik M. Wiśniowska, B.; Paśko, P. From probiotics to psychobiotics – the gut-brain axis in psychiatric disorders. Benef. Microbes. 2020;11(8):717–732. doi: 10.3920/BM2020.0063. - DOI - PubMed
    1. Sharma R., Gupta D., Mehrotra R., Mago P. Psychobiotics: the next-generation probiotics for the brain. Curr. Microbiol. 2021;78(2):449–463. doi: 10.1007/s00284-020-02289-5. - DOI - PubMed
    1. Appleton J. The gut-brain axis: influence of microbiota on mood and mental health. Integr. Med. (Encinitas) 2018;17(4):28–32. - PMC - PubMed