Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Jun;73(2):123-6.
doi: 10.1007/BF00291600.

Choroideremia-locus maps between DXS3 and DXS11 on Xq

A Gal, F Brunsmann, D Hogenkamp, K Rüther, D Ahlert, T F Wienker, W Hammerstein, I H Pawlowitzki

Choroideremia-locus maps between DXS3 and DXS11 on Xq

A Gal et al. Hum Genet. 1986 Jun.

Abstract

Choroideremia is a progressive tapetochoroidal dystrophy with X-linked transmission leading frequently to blindness in affected males. The choroideremia-locus (TCD) has recently been assigned to the long arm of the X chromosome by linkage to polymorphic DNA markers. In order to further define the location of the gene defect, two families segregating for choroideremia were examined for DNA restriction fragment length polymorphisms. A search was undertaken for linkage with cloned DNA probes from the proximal short and long arm as well as from the mid-portion of the long arm of the X chromosome. Our data suggest that the most plausible gene order on the Xq is: Xcen-DXYS1-DXS3-TCD-DXS11-Xqter.

PubMed Disclaimer

References

    1. Acta Ophthalmol (Copenh). 1968;46(1):79-82 - PubMed
    1. Trans Am Ophthalmol Soc. 1969;67:142-95 - PubMed
    1. Am J Hum Genet. 1984 May;36(3):546-64 - PubMed
    1. Science. 1985 Nov 15;230(4727):753-8 - PubMed
    1. Hum Genet. 1985;70(1):38-42 - PubMed

Publication types