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. 2023 Oct;45(10):2533-2543.
doi: 10.1002/hed.27477. Epub 2023 Aug 8.

Indications for sentinel lymph node biopsy in node-negative oral cancers

Taijiro Ozawa  1 , Isao Oze  2 , Takashi Matsuzuka  3 , Eiichi Sasaki  4 , Junkichi Yokoyama  5 , Yoshie Sano  6 , Masayuki Tomifuji  7 , Koji Araki  7 , Yasunao Kogashiwa  8 , Ichiro Tateya  9 , Shinya Agena  10 , Tomohiro Sakashita  11 , Hidenori Tsuzuki  12 , Hoshino Terada  13 , Hidenori Suzuki  13 , Daisuke Nishikawa  13 , Shintarou Beppu  13 , Takuma Matoba  14 , Nobuaki Mukoyama  15 , Keisuke Oguri  16 , Yasuhisa Hasegawa  3
Affiliations

Indications for sentinel lymph node biopsy in node-negative oral cancers

Taijiro Ozawa et al. Head Neck. 2023 Oct.

Erratum in

Abstract

Background: We aimed to define the indications for sentinel lymph node biopsy (SLNB), the third option for cervical treatment in oral cancer with negative cervical lymph nodes.

Methods: The greatest depth of invasion (DOI) and long diameter (LD) of the primary site were used as exposures. SLN metastasis was considered the outcome.

Results: In three trials conducted between 2009 and 2016, 158 patients were eligible and reassigned to this study group. The scatterplot based on the respective values of DOI and LD would eventually be divided into three sections. In cases of sections T1, T2, and T3, the proportions of SLN metastasis positivity were 21.3%, 35.3%, and 51.2%, respectively. In certain cases of T1 with 2 mm < DOI ≤ 5 mm and 8 mm < LD ≤ 20 mm, the proportion of SLN metastasis positivity was 40.9%.

Conclusions: SLNB-navigated or assisted neck dissection can be added as an effective procedure for N0 neck control.

Keywords: indication; neck dissection; node-negative; oral cavity cancer; sentinel lymph node biopsy.

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References

REFERENCES

    1. National Comprehensive Cancer Network (NCCN). Clinical Practice Guidelines in Oncology, Head and Neck Cancers Version 3.2021. 2021. Accessed September 19, 2021. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1437
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