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Comment
. 2023 Aug 7;33(15):R812-R814.
doi: 10.1016/j.cub.2023.06.053.

Macropinocytosis: Blowing bubbles

Joel A Swanson  1
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Free article
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Macropinocytosis: Blowing bubbles

Joel A Swanson. Curr Biol. .
Free article

Abstract

Macropinocytosis is a form of endocytosis in which cells engulf relatively large quantities of extracellular fluid through cup-shaped invaginations of the plasma membrane. New work shows that macropinosome closure occurs without a localized constriction of actin filaments, indicating that membrane tension drives cup closure.

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Conflict of interest statement

Declaration of interests The author declares no competing interests.

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