Under-fuelling the fire: mitochondrial implications for energy deficiency and muscle protein synthesis
- PMID: 37555351
- DOI: 10.1113/JP285175
Under-fuelling the fire: mitochondrial implications for energy deficiency and muscle protein synthesis
Keywords: low energy availability; mitochondrial function; muscle protein synthesis.
Comment on
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Low energy availability reduces myofibrillar and sarcoplasmic muscle protein synthesis in trained females.J Physiol. 2023 Aug;601(16):3481-3497. doi: 10.1113/JP284967. Epub 2023 Jun 29. J Physiol. 2023. PMID: 37329147 Clinical Trial.
References
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- Areta, J. L., Burke, L. M., Camera, D. M., West, D. W. D., Crawshay, S., Moore, D. R., Stellingwerff, T., Phillips, S. M., Hawley, J. A., & Coffey, V. G. (2014). Reduced resting skeletal muscle protein synthesis is rescued by resistance exercise and protein ingestion following short-term energy deficit. American Journal of Physiology. Endocrinology and Metabolism, 306(8), E989-E997.
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- Flockhart, M., Nilsson, L. C., Tais, S., Ekblom, B., Apró, W., & Larsen, F. J. (2021). Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers. Cell Metabolism, 33(5), 957-970.e6.
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- Oxfeldt, M., Phillips, S. M., Andersen, O. E., Johansen, F. T., Bangshaab, M., Risikesan, J., McKendry, J., Melin, A. K., & Hansen, M. (2023). Low energy availability reduces myofibrillar and sarcoplasmic muscle protein synthesis in trained females. The Journal of Physiology, 601(16), 3481-3497.
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- Petrick, H. L., Handy, R. M., Vachon, B., Frangos, S. M., Holwerda, A. M., Gijsen, A. P., Senden, J. M., van Loon, L. J. C., & Holloway, G. P. (2023). Dietary nitrate preserves mitochondrial bioenergetics and mitochondrial protein synthesis rates during short-term immobilization in mice. The Journal of Physiology. Advance online publication. https://doi.org/10.1113/JP284701
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- Saxton, R. A., & Sabatini, D. M. (2017). mTOR signaling in growth, metabolism, and disease. Cell, 168(6), 960-976.
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