Idiopathic hypersomnia: the long journey from classification to an efficacious drug

Affiliations

Comment

Geert Mayer et al. J Clin Sleep Med. 2023.

. 2023 Oct 1;19(10):1709-1710.

doi: 10.5664/jcsm.10776.

No abstract available

Conflict of interest statement

This was not an industry-supported study. The authors report no conflicts of interest.

Long-term efficacy and safety of low-sodium oxybate in an open-label extension period of a placebo-controlled, double-blind, randomized withdrawal study in adults with idiopathic hypersomnia.
Morse AM, Dauvilliers Y, Arnulf I, Thorpy MJ, Foldvary-Schaefer N, Chandler P, Chen A, Hickey L, Black J, Bogan RK. Morse AM, et al. J Clin Sleep Med. 2023 Oct 1;19(10):1811-1822. doi: 10.5664/jcsm.10698. J Clin Sleep Med. 2023. PMID: 37409509 Free PMC article. Clinical Trial.

1. Morse AM , Dauvilliers Y , Arnulf I , et al. . Long-term efficacy and safety of low-sodium oxybate in an open-label extension period of a placebo-controlled, double-blind, randomized withdrawal study in adults with idiopathic hypersomnia . J Clin Sleep Med. 2023. ; 19 ( 10 ): 1811 – 1822 . - PMC - PubMed
1. Roth B . [Sleep drunkenness and sleep paralysis] . Cesk Neurol. 1956. ; 19 ( 1 ): 48 – 58 . - PubMed
1. American Academy of Sleep Medicine . International Classification of Sleep Disorders. 3rd ed. Darien, IL: : American Academy of Sleep Medicine; ; 2014. .
1. Lammers GJ , Bassetti CLA , Dolenc-Groselj L , et al. . Diagnosis of central disorders of hypersomnolence: a reappraisal by European experts . Sleep Med Rev. 2020. ; 52 : 101306 . - PubMed
1. Ruoff C , Pizza F , Trotti LM , et al. . The MSLT is repeatable in narcolepsy type 1 but not narcolepsy type 2: a retrospective patient study . J Clin Sleep Med. 2018. ; 14 ( 1 ): 65 – 74 . - PMC - PubMed