Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Oct;15(5):880-892.
doi: 10.1007/s12975-023-01182-0. Epub 2023 Aug 9.

Application of Nanozymes and its Progress in the Treatment of Ischemic Stroke

Qing Han  1   2 , Chengcheng Wang  2 , Jian Liu  2 , Cai Wang  2 , Hongming Zhang  1   2 , Qingbin Ni  3 , Jingyi Sun  4 , Ying Wang  5 , Baoliang Sun  6   7
Affiliations
Review

Application of Nanozymes and its Progress in the Treatment of Ischemic Stroke

Qing Han et al. Transl Stroke Res. 2024 Oct.

Abstract

Nanozymes are a new kind of material which has been applied since the beginning of this century, and its birth has promoted the development of chemistry, materials science, and biology. Nanozymes can be used as a substitute for natural enzyme and has a wide range of applications; therefore, it has attracted extensive attention from all sectors of the community, and the number of studies has constantly increasing. In this paper, we introduced the outstanding achievements in the field of nanozymes in recent years from the main function, the construction of nanozyme-based biosensors, and the treatment of ischemic stroke, and we also illustrated the internal mechanism and the catalytic principle. In the end, the obstacles and challenges in the future development of nanozymes were proposed.

Keywords: Biosensor; Ischemic stroke; Nanozymes; Oxidoreductase; Reactive oxygen species.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Wu Y, Xu W, Jiao L, et al. Defect engineering in nanozymes. Mater Today. 2022;52:327–47. https://doi.org/10.1016/j.mattod.2021.10.032 . - DOI
    1. Zhang X, Wu D, Zhou X, et al. Recent progress in the construction of nanozyme-based biosensors and their applications to food safety assay. Trends Analyt Chem. 2019;121:115668. https://doi.org/10.1016/j.trac.2019.115668 . - DOI
    1. Gao L, Zhuang J, Nie L, et al. Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat Nanotechnol. 2007;2:577–83. https://doi.org/10.1038/nnano.2007.260 . - DOI - PubMed
    1. Wang GL, Jin LY, Dong YM, et al. Intrinsic enzyme mimicking activity of gold nanoclusters upon visible light triggering and its application for colorimetric trypsin detection. Biosens Bioelectron. 2015;64:523–9. https://doi.org/10.1016/j.bios.2014.09.071 . - DOI - PubMed
    1. Kumawat M, Madhyastha H, Singh M, et al. Functional silver nanozymes regulate cell inflammatory cytokines expression in mouse macrophages. Colloids Surf A Physicochem Eng Asp. 2022;650. https://doi.org/10.1016/j.colsurfa.2022.129294 .

LinkOut - more resources