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Comment
. 2023 Jan-Dec;15(1):2244718.
doi: 10.1080/19490976.2023.2244718.

The importance of the gut microbiome in the pathogenesis and transmission of SARS-CoV-2

Carlo Brogna  1 , Valentina Viduto  2 , Mark Fabrowski  3 , Simone Cristoni  4 , Giuliano Marino  5 , Luigi Montano  6 , Marina Piscopo  7
Affiliations
Comment

The importance of the gut microbiome in the pathogenesis and transmission of SARS-CoV-2

Carlo Brogna et al. Gut Microbes. 2023 Jan-Dec.

Abstract

Zhou et al. study nicely traces a significant topic in COVID-19 infection: the persistence of the virus within the intestinal tract. Many pathological mechanisms have been noted in the current literature about the mode of infection and propagation of SARS-CoV-2 in the human body. Nevertheless, there are still many concerns about this: only some things seem well understood. We present a different point of view by illustrating the importance of the gut microbiome in the pathogenesis of COVID-19 disorders.

Keywords: COVID-19; MIS-C; SARS-CoV-2; gut microbiome.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
The bacteriophagic behavior of SARS-CoV-2. Panels a and b: Transmission electron microscope images (panels a and B, TEM FEI, Thermo Fisher Tecnai G2 operating at 120 kV) show SARS-CoV-2 (indicated by black arrows) inside two bacteria. Panel C: The proteomic profile at mass spectrometry confirms the presence of an abundance of SARS-CoV-2 proteins; Peptide mapping of SARS-CoV-2 spike protein was acquired by means of liquid chromatography-mass spectrometry associated with 14N and 15N profiles and performed on an aliquot of bacteria, derived from the human gut microbiome, culture after 7 days with the presence of SARS-CoV-2. Images obtained for the gentle concession of the authors.
See this image and copyright information in PMC

Comment on

References

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