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Review
. 2023 Jul;16(7):26-33.

Evaluation of Current Literature on Complications Secondary to Lip Augmentation Following Dermal Filler Injection

Zoya Diwan  1 , Sanjay Trikha  2 , Sepideh Etemad-Shahidi  3 , Nina Parrish  4 , Christopher Rennie  5
Affiliations
Review

Evaluation of Current Literature on Complications Secondary to Lip Augmentation Following Dermal Filler Injection

Zoya Diwan et al. J Clin Aesthet Dermatol. 2023 Jul.

Abstract

Background: The current popularity of dermal filler treatments as an alternative to invasive surgical cosmetic procedures has led to an increase in filler-related complications. Lip filler treatments are among the most sought-after injectable treatments and a thorough understanding of the complications of lip filler injections, and their management, is essential for any practitioner.

Objective: The aim of this review is to evaluate the current literature on complications secondary to lip augmentation following non-permanent dermal fillers.

Methods: A thorough MEDLINE literature search of keywords, including lip filler, augmentation, injection, filler, dermal filler, and complications, was completed to collate cases of complications secondary to lip filler injections.

Results: Of our 53 cases that were studied, 82 complications were reported. Our review and evaluation of these cases showed that HA filler was most commonly used in this region, alone or in combination with other soft tissue fillers. The majority of complications resulted from HA involvement, however its frequency of use likely accounts for this. Across all three filler types, the most common complication was nodule formation. Other complications, such as migration, discoloration and herpetic outbreaks, have been linked with filler placement in the lip area.

Conclusion: It is clear that filler treatments carry a variety of risks, thus it becomes of utmost importance to truly understand the product we are working with, its properties, its associated risks, and how to manage those risks. We have to ensure that patients are adequately informed about the risks associated, and understand what those risks entail.

Keywords: Hyaluronic acid; complicatios; cosmetic complications; dermal filler; lip filler; lip filler complications.

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Conflict of interest statement

DISCLOSURES: The authors report no conflicts of interest relevant to the content of this article.

Figures

FIGURE 1.
FIGURE 1.
Complications sub-groups. 50.9% were hyaluronic acid (HA) only, 11.3% were mixed HA and another non-permanent filler and 37.7% were non-HA fillers
FIGURE 2.
FIGURE 2.
Complications of the hyaluronic acid (HA)-only subgroup; "Types of nodules" include nodules, lumps, masses, abscess, granulomatous reaction and lesions
FIGURE 3.
FIGURE 3.
Complications of the mixed hyaluronic acid (HA) and non-permanent filler subgroupl; “Types of nodules” include nodules, lumps, masses, abscess, granulomatous reaction and lesions
FIGURE 4.
FIGURE 4.
Complications of the non-hyaluronic acid (HA) filler subgroup; “Types of nodules” include nodules, lumps, masses, abscess, granulomatous reaction and lesions
See this image and copyright information in PMC

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