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Case Reports
. 2023 Jul;14(7):255-259.
doi: 10.14740/jmc4121. Epub 2023 Jul 31.

Mucosa-Associated Lymphoid Tissue Lymphoma of the Ascending Colon Successfully Removed With Endoscopic Submucosal Dissection

Grigorios Petrousis  1 , Simone Ignatova  2 , Maria Xintara  3 , Spyridon Vrakas  4 , Dimitrios Karapiperis  1
Affiliations
Case Reports

Mucosa-Associated Lymphoid Tissue Lymphoma of the Ascending Colon Successfully Removed With Endoscopic Submucosal Dissection

Grigorios Petrousis et al. J Med Cases. 2023 Jul.

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma is a type of non-Hodgkin lymphoma with characteristic histopathological features and can occur in various extranodal sites, including the gastrointestinal tract. While gastric MALT lymphoma has been extensively researched, primary lymphoma presentation in the colorectal mucosa is rare and lacks any association with Helicobacter pylori infection. Furthermore, there are currently no standardized treatment guidelines for this condition. This report presents a rare case of primary MALT lymphoma that manifested as a broad-based polyp. The diagnosis was confirmed through histopathological and immunohistochemical examination, and the polyp was resected endoscopically with the endoscopic submucosal dissection technique.

Keywords: Ascending colon; Colonoscopy; Endoscopic submucosal dissection; Mucosa-associated lymphoid tissue lymphoma.

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Conflict of interest statement

None to declare.

Figures

Figure 1
Figure 1
Colonoscopy image of the broad-based polyp in the ascending colon.
Figure 2
Figure 2
Histologic findings in hematoxylin and eosin stain revealing a vaguely nodular infiltration of small- to medium-sized lymphocytes with only a few scattered atypical cells in the mucosa and submucosa.
Figure 3
Figure 3
(a) Immunohistochemical stain for CD20 showed that the infiltrate dominates almost entirely of CD20+ B cells. (b) Immunohistochemistry was positive for Bcl-2.
See this image and copyright information in PMC

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