Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae

Thomas S Postler¹, Martin Beer², Bradley J Blitvich³, Jens Bukh^{4

5}, Xavier de Lamballerie⁶, J Felix Drexler⁷, Allison Imrie⁸, Amit Kapoor^{9

10}, Galina G Karganova¹¹, Philippe Lemey¹², Volker Lohmann¹³, Peter Simmonds¹⁴, Donald B Smith¹⁴, Jack T Stapleton^{15

16}, Jens H Kuhn¹⁷

Affiliations

¹ Vaccine Design and Development Laboratory, International AIDS Vaccine Initiative, Brooklyn, NY, USA.
² Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald, Insel Riems, Germany.
³ Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA.
⁴ Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
⁵ CO-HEP, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
⁶ Unité des Virus Émergents (Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
⁷ Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
⁸ School of Biomedical Sciences, University of Western Australia, Nedlands, WA, Australia.
⁹ Center for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
¹⁰ Department of Pediatrics, College of Medicine and Public Health, The Ohio State University, Columbus, OH, USA.
¹¹ Laboratory of Biology of Arboviruses, FSASI "Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of RAS" (Chumakov Institute of Poliomyelitis and Viral Encephalitides), Moscow, Russia.
¹² Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.
¹³ Department of Infectious Diseases, Molecular Virology, Heidelberg University, Heidelberg, Germany.
¹⁴ Nuffield Department of Medicine, University of Oxford, Oxford, UK.
¹⁵ Medicine Service, Iowa City Veterans Administration Healthcare, Iowa City, IA, USA.
¹⁶ Departments of Internal Medicine, Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
¹⁷ Integrated Research Facility at Fort Detrick (IRF-Frederick), Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), B-8200 Research Plaza, Fort Detrick, Frederick, MD, 21702, USA. kuhnjens@mail.nih.gov.

PMID: 37561168
DOI: 10.1007/s00705-023-05835-1

Review

Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae

Thomas S Postler et al. Arch Virol. 2023.

. 2023 Aug 10;168(9):224.

doi: 10.1007/s00705-023-05835-1.

Authors

Affiliations

¹ Vaccine Design and Development Laboratory, International AIDS Vaccine Initiative, Brooklyn, NY, USA.
² Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald, Insel Riems, Germany.
³ Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA.
⁴ Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
⁵ CO-HEP, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
⁶ Unité des Virus Émergents (Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
⁷ Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
⁸ School of Biomedical Sciences, University of Western Australia, Nedlands, WA, Australia.
⁹ Center for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
¹⁰ Department of Pediatrics, College of Medicine and Public Health, The Ohio State University, Columbus, OH, USA.
¹¹ Laboratory of Biology of Arboviruses, FSASI "Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of RAS" (Chumakov Institute of Poliomyelitis and Viral Encephalitides), Moscow, Russia.
¹² Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.
¹³ Department of Infectious Diseases, Molecular Virology, Heidelberg University, Heidelberg, Germany.
¹⁴ Nuffield Department of Medicine, University of Oxford, Oxford, UK.
¹⁵ Medicine Service, Iowa City Veterans Administration Healthcare, Iowa City, IA, USA.
¹⁶ Departments of Internal Medicine, Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
¹⁷ Integrated Research Facility at Fort Detrick (IRF-Frederick), Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), B-8200 Research Plaza, Fort Detrick, Frederick, MD, 21702, USA. kuhnjens@mail.nih.gov.

PMID: 37561168
DOI: 10.1007/s00705-023-05835-1

Abstract

This review provides a summary of the recently ratified changes to genus and species nomenclature within the virus family Flaviviridae along with reasons for these changes. First, it was considered that the vernacular terms "flaviviral", "flavivirus", and "flaviviruses" could under certain circumstances be ambiguous due to the same word stem "flavi" in the taxon names Flaviviridae and Flavivirus; these terms could either have referred to all viruses classified in the family Flaviviridae or only to viruses classified in the included genus Flavivirus. To remove this ambiguity, the genus name Flavivirus was changed to Orthoflavivirus by the International Committee on Taxonomy of Viruses (ICTV). Second, all species names in the family were changed to adhere to a newly ICTV-mandated binomial format (e.g., Orthoflavivirus zikaense, Hepacivirus hominis) similar to nomenclature conventions used for species elsewhere in biology. It is important to note, however, that virus names remain unchanged. Here we outline the revised taxonomy of the family Flaviviridae as approved by the ICTV in April 2023.

PubMed Disclaimer

References

1. International Committee on Taxonomy of Viruses (ICTV) (2023) Virus taxonomy: 2022 Release (MSL #38). https://talk.ictvonline.org/taxonomy/ . Accessed 17 July 2023
1. International Committee on Taxonomy of Viruses (ICTV) (2023) Approved proposals. https://ictv.global/files/proposals/approved . Accessed 17 July 2023
1. International Committee on Taxonomy of Viruses (ICTV) (2023) ICTV Code. The International Code of Virus Classification and Nomenclature (ICVCN). March 2021. https://ictv.global/about/code . Accessed 17 July 2023
1. Postler TS, Rubino L, Adriaenssens EM, Dutilh BE, Harrach B, Junglen S, Kropinski AM, Krupovic M, Wada J, Crane A, Kuhn JH, Mushegian A, Rūmnieks J, Sabanadzovic S, Simmonds P, Varsani A, Zerbini FM, Callanan J, Draper LA, Hill C, Stockdale SR (2022) Guidance for creating individual and batch latinized binomial virus species names. J Gen Virol 103:001800 - DOI - PubMed - PMC
1. Siddell SG, Smith DB, Adriaenssens E, Alfenas-Zerbini P, Dutilh BE, Garcia ML, Junglen S, Krupovic M, Kuhn JH, Lambert AJ, Lefkowitz EJ, Łobocka M, Mushegian AR, Oksanen HM, Robertson DL, Rubino L, Sabanadzovic S, Simmonds P, Suzuki N, Van Doorslaer K, Vandamme AM, Varsani A, Zerbini FM (2023) Virus taxonomy and the role of the International Committee on Taxonomy of Viruses (ICTV). J Gen Virol 104:001840 - DOI - PubMed - PMC

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions

Grants and funding

LinkOut - more resources

Full Text Sources
- Springer
Miscellaneous
- NCI CPTAC Assay Portal

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae

Affiliations

Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae

Authors

Affiliations

Abstract

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Miscellaneous