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Comparison of pediatric ventriculo-peritoneal shunt infections arising in antibiotic-impregnated and standard catheters: a multicenter observational study
Comparison of pediatric ventriculo-peritoneal shunt infections arising in antibiotic-impregnated and standard catheters: a multicenter observational study
Infections of standard and antibiotic-impregnated…
Figure 1
Infections of standard and antibiotic-impregnated ventricular shunt catheters (AIVSCs). (A) The proportion of…
Figure 1
Infections of standard and antibiotic-impregnated ventricular shunt catheters (AIVSCs). (A) The proportion of AIVSC infections increased over calendar time. (B) The ratio of staphylococci to other microorganisms did not change significantly over time. (C) The distribution of pathogens was not statistically significantly different. (D) The time from shunt insertion to infection in AIVSCs vs standard shunts for staphylococci and for other organisms. (E) The ratio of incident staphylococcal to other infections in the first month among patients with AIVSCs and in the second month. AIVSCs, antibiotic-impregnated ventricular shunt catheters; CoNS, coagulase-negative staphylococci; GN, Gram-negative;.GP, Gram-positive; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-susceptible Staphylococcus aureus.
Arditi M, Yogev R. In vitro interaction between rifampin and clindamycin against pathogenic coagulase-negative staphylococci. Antimicrob Agents Chemother 1989;33:245–7. 10.1128/AAC.33.2.245
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Mallucci CL, Jenkinson MD, Conroy EJ, et al. . Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation. Lancet 2019;394:1530–9. 10.1016/S0140-6736(19)31603-4
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Raffa G, Marseglia L, Gitto E, et al. . Antibiotic-impregnated catheters reduce ventriculoperitoneal shunt infection rate in high-risk newborns and infants. Childs Nerv Syst 2015;31:1129–38. 10.1007/s00381-015-2685-7
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Hayhurst C, Cooke R, Williams D, et al. . The impact of antibiotic-impregnated catheters on shunt infection in children and neonates. Childs Nerv Syst 2008;24:557–62. 10.1007/s00381-007-0521-4
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Parker SL, Attenello FJ, Sciubba DM, et al. . Comparison of shunt infection incidence in high-risk subgroups receiving antibiotic-impregnated versus standard shunts. Childs Nerv Syst 2009;25:77–83. 10.1007/s00381-008-0743-0
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