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. 2023 Jul 27;12(15):4930.
doi: 10.3390/jcm12154930.

Feasibility and Efficacy of Transcatheter Tricuspid Valve Repair in Patients with Cardiac Implanted Electrical Devices and Trans-Tricuspid Leads

Mhd Nawar Alachkar  1 , Steffen Schnupp  1 , Astrid Eichelsdoerfer  1 , Andrea Milzi  2 , Hesham Mady  1 , Basem Salloum  1 , Osama Bisht  1 , Mohammed Cheikh-Ibrahim  1 , Mathias Forkmann  1 , Lukas Krygier  1 , Christian Mahnkopf  1
Affiliations

Feasibility and Efficacy of Transcatheter Tricuspid Valve Repair in Patients with Cardiac Implanted Electrical Devices and Trans-Tricuspid Leads

Mhd Nawar Alachkar et al. J Clin Med. .

Abstract

Background: Transcatheter tricuspid valve repair using the edge-to-edge-technique (TEER) has emerged as an alternative therapy in patients with severe tricuspid regurgitation (TR) and high surgical risk. This study aimed to evaluate the feasibility and efficacy of tricuspid valve TEER in patients with cardiac implanted electric devices (CIEDs).

Methods: All patients who underwent tricuspid valve TEER at our center were retrospectively included. Patients were classified according to the presence of CIEDs. Procedure success was defined as implantation of at least one clip and the reduction of TR of at least one grade. Procedure success and intrahospital outcome were compared between the two groups.

Results: One-hundred and six consecutive patients underwent tricuspid TEER (age 80.1 ± 6.4 years, male = 42; 39.6%). Among them, 25 patients (23.6%, age 80.6 ± 7.3 years, male = 14; 56%) had CIEDs. Patients with CIEDs had a significantly lower left ventricular ejection fraction (LV-EF) compared to those without CIEDs (47.2 ± 15% vs. 56.2 ± 8.2%, p = 0.004, respectively). Moreover, arterial hypertension was more common in patients with CIEDs (96% vs. 79%, p = 0.048). The success of the procedure did not differ between the non-CIED vs. CIED group (93.8% vs. 92%, p = 0.748). Furthermore, the number and position of implanted clips, the duration of the procedure, the post-procedural pressure gradient across the tricuspid valve, and post-procedural TR severity were comparable between both groups.

Conclusion: Tricuspid valve TEER is feasible and efficient in patients with CIEDs. The success of the procedure, as well as the intrahospital outcome were comparable between patients with and without CIEDs.

Keywords: cardiac implanted electrical devices; transcatheter tricuspid valve repair; tricuspid regurgitation.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Transgastric en face view (upper panel) and mid-esophageal view (lower panel) of tricuspid valve in a patient with severe TR before and after TEER with implantation of two TriClip® devices.
See this image and copyright information in PMC

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