New Synthetic Methodology for Drug-like Molecules
- PMID: 37570616
- PMCID: PMC10419429
- DOI: 10.3390/molecules28155632
New Synthetic Methodology for Drug-like Molecules
Abstract
The field of synthetic methodology plays a pivotal role in the quest for safe and effective drugs [...].
Conflict of interest statement
The author declares no conflict of interest.
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References
-
- Chernov S.V., Shul’ts E.E., Shakirov M.M., Tolstikov G.A. Synthetic transformations of higher terpenoids: XII. Transformation of lambertianic acid into 14, 16-epoxyabietane diterpenoids. Russ. J. Org. Chem. 2006;42:36–41. doi: 10.1134/S1070428006010064. - DOI
-
- Kharitonov Y.V., Shul’ts E.E., Rybalova T.V., Pavlova A.V., Tolstikova T.G. Synthetic Transformations of Higher Terpenoids. 40. Synthesis and Assessment of Analgesic Activity of N-Containing Derivatives of Lambertianic Acid. Chem. Nat. Compd. 2021;57:879–886. doi: 10.1007/s10600-021-03502-y. - DOI
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