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. 2024 Feb 14;229(2):457-461.
doi: 10.1093/infdis/jiad333.

Detection of Rotavirus in Respiratory Specimens From Bangladeshi Children Aged <2 Years Hospitalized for Acute Gastroenteritis

Syed Moinuddin Satter  1 , Eric Katz  2 , Mohammad Enayet Hossain  1 , Farzana Fariha  1 , Muhammad Talha  1 , Sarah L Smart  2 , Michael D Bowen  2 , Mustafizur Rahman  1 , Umesh D Parashar  2 , Margaret M Cortese  2
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Detection of Rotavirus in Respiratory Specimens From Bangladeshi Children Aged <2 Years Hospitalized for Acute Gastroenteritis

Syed Moinuddin Satter et al. J Infect Dis. .

Abstract

To examine the potential for respiratory transmission of rotavirus, we systematically assessed if rotavirus RNA is detectable by real-time quantitative reverse transcription-polymerase chain reaction from nasal and oropharyngeal swab specimens of Bangladeshi children with acute rotavirus gastroenteritis. Forehead swabs were collected to assess skin contamination. Among 399 children aged <2 years hospitalized for gastroenteritis during peak rotavirus season, rotavirus RNA was detected in stool, oral, nasal and forehead swab specimens of 354 (89%). A subset was genotyped; genotype was concordant within a child's specimen set and several different genotypes were detected across children. These findings support possible respiratory transmission of rotavirus and warrant further investigation.

Keywords: gastroenteritis; replication; respiratory; rotavirus; transmission.

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Conflict of interest statement

Potential conflicts of interest . The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

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