Engineering the endometrium

Shelly R Peyton¹

Affiliations

Affiliation

¹ Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA 01003, USA; Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA 01003, USA; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA 01003, USA; Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA 01003, USA. Electronic address: speyton@umass.edu.

PMID: 37572649
DOI: 10.1016/j.medj.2023.07.009

Free article

Comment

Engineering the endometrium

Shelly R Peyton. Med. 2023.

Free article

. 2023 Aug 11;4(8):495-496.

doi: 10.1016/j.medj.2023.07.009.

Author

Shelly R Peyton¹

Affiliation

¹ Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA 01003, USA; Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA 01003, USA; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA 01003, USA; Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA 01003, USA. Electronic address: speyton@umass.edu.

PMID: 37572649
DOI: 10.1016/j.medj.2023.07.009

Abstract

Endometrial tissue is a dynamic environment that regenerates alongside the menstrual cycle and in response to sex hormones. This month in Med, Gnecco and colleagues¹ present an innovative, synthetic model of endometrial environment that supports long-term cultures, simulates a 28-day menstrual cycle, and could be employed to investigate reproductive pathophysiology.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk.
Gnecco JS, Brown A, Buttrey K, Ives C, Goods BA, Baugh L, Hernandez-Gordillo V, Loring M, Isaacson KB, Griffith LG. Gnecco JS, et al. Med. 2023 Aug 11;4(8):554-579.e9. doi: 10.1016/j.medj.2023.07.004. Med. 2023. PMID: 37572651 Free PMC article.

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Engineering the endometrium

Affiliation

Engineering the endometrium

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Affiliation

Abstract

Conflict of interest statement

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Publication types

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LinkOut - more resources

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