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Review
. 2024 May 1;19(5):641-649.
doi: 10.2215/CJN.0000000000000280. Epub 2023 Aug 14.

Peritoneal Dialysis-Related Infections

Yeoungjee Cho  1   2 , Kai-Ming Chow  3   4 , Philip Kam-Tao Li  3   4 , Naomi Runnegar  5 , David W Johnson  1   2
Affiliations
Review

Peritoneal Dialysis-Related Infections

Yeoungjee Cho et al. Clin J Am Soc Nephrol. .

Abstract

Peritoneal dialysis (PD) represents an important treatment choice for patients with kidney failure. It allows them to dialyze outside the hospital setting, facilitating enhanced opportunities to participate in life-related activities, flexibility in schedules, time and cost savings from reduced travel to dialysis centers, and improved quality of life. Despite its numerous advantages, PD utilization has been static or diminishing in parts of the world. PD-related infection, such as peritonitis, exit-site infection, or tunnel infection, is a major concern for patients, caregivers, and health professionals-which may result in hesitation to consider this as treatment or to cease therapy when these complications take place. In this review, the definition, epidemiology, risk factors, prevention, and treatment of PD-related infection on the basis of the contemporary evidence will be described.

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Conflict of interest statement

Y. Cho has received consultancy fees, research grants, and speaker's honoraria from Baxter Healthcare, Bupa, and Fresenius Medical Care. D.W. Johnson has received consultancy fees, research grants, speaker’s honoraria, and travel sponsorships from Baxter Healthcare and Fresenius Medical Care; consultancy fees from AstraZeneca, AWAK, and Bayer; speaker’s honoraria from BI & Lilly and ONO; and travel sponsorships from Amgen and Ono. All remaining authors have nothing to disclose.

Figures

Figure 1
Figure 1
Time-specific peritonitis definitions. PD, peritoneal dialysis.
Figure 2
Figure 2
The process of continuous quality improvement to address the burden of peritoneal dialysis–related infection.
Figure 3
Figure 3
Approach to treating PD-related infections. Treatment algorithm of (A) PD-related peritonitis and (B) PD catheter exit-site infection., *PD patients are recommended to receive concomitant antifungal prophylaxis. IP, intraperitoneal; MRSA, methicillin-resistant staphylococcus aureus.
See this image and copyright information in PMC

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