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Case Reports
. 2023 Jul-Sep;39(3):242-244.
doi: 10.4103/iju.iju_398_22. Epub 2023 Jun 30.

Human papillomavirus infection causing refractory lower urinary tract symptoms in a young female

Vagan Barsegian  1 , Inga Kosova  1
Affiliations
Case Reports

Human papillomavirus infection causing refractory lower urinary tract symptoms in a young female

Vagan Barsegian et al. Indian J Urol. 2023 Jul-Sep.

Abstract

We describe a rare case of refractory lower urinary tract symptoms in a young woman caused by human papillomavirus (HPV) infection. Concurrently, vulvar and vaginal warts were present, particularly near the external urethral meatus. Biopsy of the whitish plaque in the trigone of the bladder demonstrated signs of HPV infection and bladder leukoplakia; polymerase chain reaction analysis of this tissue was positive for HPV16. Systemic and local treatments for HPV infection were prescribed. All symptoms resolved. Follow-up examination revealed negative HPV DNA in the bladder tissue.

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Conflict of interest statement

Conflicts of interest: There are no conflicts of interest.

Figures

Figure 1
Figure 1
Cystoscopy demonstrating a whitish plaque in the trigone of the bladder
Figure 2
Figure 2
Histology of the bladder tissue biopsy revealed papillary hyperplasia of squamous epithelium with koilocytosis and scant lymphocytic infiltration (H and E, ×20)
See this image and copyright information in PMC

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