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Comparative Study
. 1986 Oct;31(10):1009-13.
doi: 10.1007/BF01300251.

Relationship between functional and histological changes in chronic pancreatitis

H A Heij, H Obertop, M van Blankenstein, F W ten Kate, D L Westbroek
Comparative Study

Relationship between functional and histological changes in chronic pancreatitis

H A Heij et al. Dig Dis Sci. 1986 Oct.

Abstract

The results of the secretin-CCK test were compared with the histological findings of pancreatic tissue resected in 25 patients with chronic pancreatitis. Secretin-CCK test results were interpreted with the use of discriminant analysis, yielding a quantitative score for each patient. Histological findings were recorded according to a semiquantitative scale. Fairly high correlation coefficients were found between secretin-CCK test results and severity of acinar atrophy and small dilatation. These findings emphasize the importance of the secretin-CCK test for diagnostic and follow-up purposes in chronic pancreatitis.

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