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Comment
. 2023 Sep;8(9):1611-1612.
doi: 10.1038/s41564-023-01445-4.

CRISPR-influenced symbiosis

Anna-Louise Reysenbach  1 , Michael P Terns  2
Affiliations
Comment

CRISPR-influenced symbiosis

Anna-Louise Reysenbach et al. Nat Microbiol. 2023 Sep.

Abstract

CRISPR systems canonically confer microorganisms with protection against invading viral DNA, plasmids and mobile genetic elements, however a multi-omics investigation of deep subsurface archaeal communities suggests that archaeal CRISPR systems might target other archaeal parasites or force a transition from parasitism to mutualism.

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Conflict of interest statement

Competing interests

The authors declare no competing interests.

Figures

Fig. 1 |
Fig. 1 |. Potential mechanisms of CRISPR-influenced symbioses.
Proposed role of CRISPR systems in the symbiosis outcomes of the archaeal host–epibiont association, ‘Ca. Altiarchaeum sp.’ and their associated epibiont, ‘Ca. Huberiarchaeum sp.’.
See this image and copyright information in PMC

Comment on

  • A predicted CRISPR-mediated symbiosis between uncultivated archaea.
    Esser SP, Rahlff J, Zhao W, Predl M, Plewka J, Sures K, Wimmer F, Lee J, Adam PS, McGonigle J, Turzynski V, Banas I, Schwank K, Krupovic M, Bornemann TLV, Figueroa-Gonzalez PA, Jarett J, Rattei T, Amano Y, Blaby IK, Cheng JF, Brazelton WJ, Beisel CL, Woyke T, Zhang Y, Probst AJ. Esser SP, et al. Nat Microbiol. 2023 Sep;8(9):1619-1633. doi: 10.1038/s41564-023-01439-2. Epub 2023 Jul 27. Nat Microbiol. 2023. PMID: 37500801

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