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Review
. 2023 Aug 12:14:21514593231195244.
doi: 10.1177/21514593231195244. eCollection 2023.

Psoas Muscle Morphology as a Sarcopenia Marker to Predict Outcomes of Geriatric Trauma Patients: A Systematic Review and Meta-analysis

Yang Wang  1 , Lei Li  1 , Qinmei Pan  1 , Ying Zhong  1 , Xinmei Zou  1
Affiliations
Review

Psoas Muscle Morphology as a Sarcopenia Marker to Predict Outcomes of Geriatric Trauma Patients: A Systematic Review and Meta-analysis

Yang Wang et al. Geriatr Orthop Surg Rehabil. .

Abstract

Objective: To provide pooled evidence on the association between central sarcopenia and risk of mortality and/or complications among geriatric patients with moderate to severe trauma.

Methods: We conducted a systematic search in PubMed, EMBASE, and Scopus databases for relevant observational studies documenting the association of central sarcopenia with the risk of mortality and/or complications in geriatric patients with moderate to severe trauma. The studies reported computerized tomography (CT) based assessments of the psoas muscle cross-sectional area. We used a random effects model for the analysis and reported effect sizes as pooled odds ratios (ORs) or hazards ratios (HRs) along with 95% confidence intervals.

Results: We analyzed data from 13 studies and found an association between the presence of psoas muscle size reduction and the risk of in-hospital mortality (OR, 1.47; 95% CI, 1.13, 1.90). In addition, we found increased risk of mortality within 24 months of follow-up in patients with sarcopenia (HR, 2.40; 95% CI, 1.11-5.17). We found each unit increase in psoas muscle cross-sectional area to be significantly associated with reduced risk of mortality within 24 months of follow-up (HR, .92; 95% CI, .90-.95). Patients with sarcopenia also had an increased risk of complications (OR, 1.69; 95% CI, 1.08-2.63).

Conclusion: Central sarcopenia, assessed using psoas muscle morphology, among geriatric patients with moderate to severe trauma appears to be significantly associated with increased risks of mortality and complications.

Keywords: complications; elderly; geriatric; meta-analysis; mortality; psoas muscle area; sarcopenia; systematic review; trauma.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Selection process of studies included in the review.
Figure 2.
Figure 2.
Risks of in-hospital mortality among elderly patients with trauma and associated sarcopenia and those without sarcopenia.
Figure 3.
Figure 3.
Risks of mortality within 24 months of follow-up after hospital discharge among elderly patients with sarcopenia and those without sarcopenia.
Figure 4.
Figure 4.
Risks of complications among elderly patients with trauma and associated sarcopenia and those without sarcopenia.
See this image and copyright information in PMC

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