Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Jul 16;15(7):e41957.
doi: 10.7759/cureus.41957. eCollection 2023 Jul.

The Potential Role of Torsemide in Optimizing Loop Diuretic Therapy for Heart Failure Patients

Affiliations
Review

The Potential Role of Torsemide in Optimizing Loop Diuretic Therapy for Heart Failure Patients

V K Chopra et al. Cureus. .

Abstract

Heart failure is associated with an increased frequency of hospitalization, reduced life span, and greater risk to public health, thus posing a challenge. In India, torsemide is one of the commonly used loop diuretics for decongestion in heart failure. However, this use of torsemide, including its dosing, and up/down titration, is based on practical experience. Loop diuretic therapy for heart failure patients poses several dilemmas due to the lack of robust evidence based on which treatment decisions can be made. To guide physicians on the optimal use of torsemide in heart failure patients with or without renal impairment, a panel of expert cardiologists and nephrologists from India convened to develop this expert opinion document for the use of torsemide. This expert opinion on torsemide will pave the way for optimal management with loop diuretic therapy in real-world heart failure patients.

Keywords: expert opinion; heart failure; loop diuretics; optimal management; torsemide.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Oral torsemide dosing algorithm
Figure 2
Figure 2. Dosing algorithms of torsemide in patients with heart failure
Figure 3
Figure 3. Parenteral torsemide-dosing algorithm

References

    1. Epidemiology and prevention in India. Huffman M, Prabhakaran D. http://archive.nmji.in/archives/Volume-23/Issue-5/Review-Article.pdf. Natl Med J India. 2010;23:283–288. - PMC - PubMed
    1. Financial burden of heart failure in a developing country: cost analysis from Manipal Heart Failure Registry, India. Singh A, Chauhan S, Devasia T, et al. J Public Health (Berl) 2021;29:585–594.
    1. Management protocols for chronic heart failure in India. Mishra S, Mohan JC, Nair T, et al. Indian Heart J. 2018;70:105–127. - PMC - PubMed
    1. 2022 AHA/ACC/HFSA guideline for the management of heart failure. Writing Committee Members. J Card Fail. 2022;28:0. - PubMed
    1. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. McDonagh TA, Metra M, Adamo M, et al. Eur Heart J. 2021;42:3599–3726. - PubMed

LinkOut - more resources