Advancements in the Worldwide Detection of Severe Fever with Thrombocytopenia Syndrome Virus Infection from 2009 to 2023

doi:10.46234/ccdcw2023.132

. 2023 Aug 4;5(31):687-693.

doi: 10.46234/ccdcw2023.132.

Advancements in the Worldwide Detection of Severe Fever with Thrombocytopenia Syndrome Virus Infection from 2009 to 2023

Lin Ai¹, Wei Wang², Zheng Teng^{1

2}

Affiliations

¹ Institute of Microbiology Laboratory, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
² Institute of Microbiology Laboratory, Shanghai Institute of Preventive Medicine, Shanghai, China.

PMID: 37593140
PMCID: PMC10427339
DOI: 10.46234/ccdcw2023.132

Advancements in the Worldwide Detection of Severe Fever with Thrombocytopenia Syndrome Virus Infection from 2009 to 2023

Lin Ai et al. China CDC Wkly. 2023.

. 2023 Aug 4;5(31):687-693.

doi: 10.46234/ccdcw2023.132.

Authors

Lin Ai¹, Wei Wang², Zheng Teng^{1

2}

Affiliations

¹ Institute of Microbiology Laboratory, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
² Institute of Microbiology Laboratory, Shanghai Institute of Preventive Medicine, Shanghai, China.

PMID: 37593140
PMCID: PMC10427339
DOI: 10.46234/ccdcw2023.132

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is a growing concern as an emerging tick-borne infectious disease originating from the SFTS virus (SFTSV), a recent addition to the Phlebovirus genus under the family of bunyaviruses. SFTS is typically identified by symptoms such as fever, thrombocytopenia, leukopenia, and gastrointestinal problems, accompanied by a potentially high case fatality rate. Thus, early and accurate diagnosis is essential for effective treatment and disease management. This review delves into the existing methodologies for SFTS detection, including pathogenic, molecular, and immunological technologies.

Keywords: Severe fever with thrombocytopenia syndrome; immunological detection; molecular detection; pathogenic detection.

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Conflict of interest statement

No conflicts of interest.

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References

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1. Li J, Li S, Yang L, Cao PF, Lu JH Severe fever with thrombocytopenia syndrome virus: a highly lethal bunyavirus. Crit Rev Microbiol. 2021;47(1):112–25. doi: 10.1080/1040841X.2020.1847037. - DOI - PubMed
1. Yu XJ, Liang MF, Zhang SY, Liu Y, Li JD, Sun YL, et al Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med. 2011;364(16):1523–32. doi: 10.1056/NEJMoa1010095. - DOI - PMC - PubMed
1. Lin TL, Ou SC, Maeda K, Shimoda H, Chan JPW, Tu WC, et al The first discovery of severe fever with thrombocytopenia syndrome virus in Taiwan. Emerg Microbes Infect. 2020;9(1):148–51. doi: 10.1080/22221751.2019.1710436. - DOI - PMC - PubMed
1. Takahashi T, Maeda K, Suzuki T, Ishido A, Shigeoka T, Tominaga T, et al The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan. J Infect Dis. 2014;209(6):816–27. doi: 10.1093/infdis/jit603. - DOI - PMC - PubMed

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[1] Li JC, Zhao J, Li H, Fang LQ, Liu W Epidemiology, clinical characteristics, and treatment of severe fever with thrombocytopenia syndrome. Infect Med. 2022;1(1):40–9. doi: 10.1016/j.imj.2021.10.001. - DOI - PMC - PubMed

[2] Li JC, Zhao J, Li H, Fang LQ, Liu W Epidemiology, clinical characteristics, and treatment of severe fever with thrombocytopenia syndrome. Infect Med. 2022;1(1):40–9. doi: 10.1016/j.imj.2021.10.001. - DOI - PMC - PubMed

[3] Li J, Li S, Yang L, Cao PF, Lu JH Severe fever with thrombocytopenia syndrome virus: a highly lethal bunyavirus. Crit Rev Microbiol. 2021;47(1):112–25. doi: 10.1080/1040841X.2020.1847037. - DOI - PubMed

[4] Li J, Li S, Yang L, Cao PF, Lu JH Severe fever with thrombocytopenia syndrome virus: a highly lethal bunyavirus. Crit Rev Microbiol. 2021;47(1):112–25. doi: 10.1080/1040841X.2020.1847037. - DOI - PubMed

[5] Yu XJ, Liang MF, Zhang SY, Liu Y, Li JD, Sun YL, et al Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med. 2011;364(16):1523–32. doi: 10.1056/NEJMoa1010095. - DOI - PMC - PubMed

[6] Yu XJ, Liang MF, Zhang SY, Liu Y, Li JD, Sun YL, et al Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med. 2011;364(16):1523–32. doi: 10.1056/NEJMoa1010095. - DOI - PMC - PubMed

[7] Lin TL, Ou SC, Maeda K, Shimoda H, Chan JPW, Tu WC, et al The first discovery of severe fever with thrombocytopenia syndrome virus in Taiwan. Emerg Microbes Infect. 2020;9(1):148–51. doi: 10.1080/22221751.2019.1710436. - DOI - PMC - PubMed

[8] Lin TL, Ou SC, Maeda K, Shimoda H, Chan JPW, Tu WC, et al The first discovery of severe fever with thrombocytopenia syndrome virus in Taiwan. Emerg Microbes Infect. 2020;9(1):148–51. doi: 10.1080/22221751.2019.1710436. - DOI - PMC - PubMed

[9] Takahashi T, Maeda K, Suzuki T, Ishido A, Shigeoka T, Tominaga T, et al The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan. J Infect Dis. 2014;209(6):816–27. doi: 10.1093/infdis/jit603. - DOI - PMC - PubMed

[10] Takahashi T, Maeda K, Suzuki T, Ishido A, Shigeoka T, Tominaga T, et al The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan. J Infect Dis. 2014;209(6):816–27. doi: 10.1093/infdis/jit603. - DOI - PMC - PubMed

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Advancements in the Worldwide Detection of Severe Fever with Thrombocytopenia Syndrome Virus Infection from 2009 to 2023

Affiliations

Advancements in the Worldwide Detection of Severe Fever with Thrombocytopenia Syndrome Virus Infection from 2009 to 2023

Authors

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Abstract

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