Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Jun 23:19:101933.
doi: 10.1016/j.jaccas.2023.101933. eCollection 2023 Aug 2.

Acute Formation of Thrombus on a Left Atrial Appendage Occlusion Device Immediately After Detachment

Affiliations
Case Reports

Acute Formation of Thrombus on a Left Atrial Appendage Occlusion Device Immediately After Detachment

Ngoda Manongi et al. JACC Case Rep. .

Abstract

Clots can form on the left atrial surface of left atrial appendage closure devices, with subsequent thromboembolization. However, we are unaware of any reports of clots forming on the devices immediately after deployment. We report a case where an acute thrombus strand formed at the tip of an occlusion device immediately after deployment. (Level of Difficulty: Intermediate.).

Keywords: COVID-19; Watchman; atrial fibrillation; drug-related thrombosis; left atrial appendage closure.

PubMed Disclaimer

Conflict of interest statement

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
3-Dimensional Transesophageal Echocardiogram Shown is releasing of the occlusion device by detaching the delivery catheter (red arrows) from the device’s threaded insert (blue arrows).
Figure 2
Figure 2
Detection of a Thrombin Strand on the Occlusion Device A new strand was noted on the device’s threaded insert shortly after detachment of the deployment catheter. (A) 3-dimensional transesophageal echocardiogram imaging. (B) Multiplanar 2-dimensional imaging.
Figure 3
Figure 3
Transesophageal Echocardiograms at 45-Day Follow-Up Visit Previously visualized strand is no longer visible after a course of anticoagulation with apixaban. No device leak at 45-day imaging. (A) 3-dimensional transesophageal echocardiogram imaging. (B) 2-dimensional transesophageal echocardiogram imaging.

References

    1. Garot P., Cormier B., Horvilleur J. Device-related thrombus after left atrial appendage closure. Interv Cardiol. 2019;14(1):42–44. - PMC - PubMed
    1. Alkhouli M., Busu T., Shah K., Osman M., Alqahtani F., Raybuck B. Incidence and clinical impact of device-related thrombus following percutaneous left atrial appendage occlusion: a meta-analysis. J Am Coll Cardiol EP. 2018;4(12):1629–1637. - PubMed
    1. Dukkipati S.R., Kar S., Holmes D.R., et al. Device-related thrombus after left atrial appendage closure: incidence, predictors, and outcomes. Circulation. 2018;138(9):874–885. - PubMed
    1. Vukomanovic D., Unzek S., Malik K., et al. Massive device-related thrombus after LAA occlusion: intraoperative insights into mechanism. J Am Coll Cardiol Case Rep. 2022;4(21):1409–1413. - PMC - PubMed
    1. Seo J.W., Kim D.Y., Yun N., Kim D.M. Coronavirus disease 2019-associated coagulopathy. Microorganisms. 2022;10(8):1556. - PMC - PubMed

Publication types

LinkOut - more resources