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. 2023 Aug 17;186(17):3523-3523.e1.
doi: 10.1016/j.cell.2023.07.031.

Herpes simplex virus gene therapy for dystrophic epidermolysis bullosa (DEB)

Alberto L Epstein  1 , Cornelia Haag-Molkenteller  2
Affiliations
Free article

Herpes simplex virus gene therapy for dystrophic epidermolysis bullosa (DEB)

Alberto L Epstein et al. Cell. .
Free article

Abstract

The FDA has recently approved Krystal biotech's beremagene geperpavec (B-VEC, Vyjuvek) to treat the wounds of dystrophic epidermolysis bullosa (DEB) patients. This represents a giant step, not only toward the treatment of this devastating disease, but also for the whole field of non-replicative (nr) recombinant HSV-1 vectors for gene therapy. To view this Bench to Bedside, open or download the PDF.

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