K-252a, a potent inhibitor of protein kinase C from microbial origin
- PMID: 3759657
- DOI: 10.7164/antibiotics.39.1059
K-252a, a potent inhibitor of protein kinase C from microbial origin
Abstract
K-252a, a metabolite isolated from the culture broth of Nocardiopsis sp. K-252a, was found to exhibit an extremely potent inhibitory activity on protein kinase C. The IC50 value was 32.9 nM.
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