Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2023 Aug 18;23(1):279.
doi: 10.1186/s12871-023-02230-w.

Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study

Misgan Mulatie Zewudie  1 , Debas Yaregal Melesse  2 , Tesera Dereje Filatie  3 , Mulualem Endeshaw Zeleke  3
Affiliations
Observational Study

Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study

Misgan Mulatie Zewudie et al. BMC Anesthesiol. .

Abstract

Background: The present study aimed to assess variables associated to ICU-mortality among patients admitted to surgical intensive care unit in Ethiopia.

Methods: A Hospital-based retrospective follow-up study was conducted on all patients who were admitted to the surgical intensive care unit. Data were extracted from patients' charts with a pretested data extraction tool, entered into Epi-data 4.6.0, and analyzed with STATA- 14. Bivariate and multivariate Cox proportional hazards regression models were fitted.

Results: Of the total study participants (388), 148 (38.1%) patients admitted to the surgical intensive care unit died during the follow-up period with a median survival time of 11 days. Potassium level < 3.5 mmol/L (adjusted hazard ratio ( AHR): 3.46, 95% CI (1.83 6.55), potassium level > 5.0 mmol/L (AHR:2.41, 95% CI (1.29-4.51), hypoxia (AHR:1.66, 95% CI (1.10-2.48), Glasgow Coma Scale (GCS) score < 9 (AHR: 4.06, 95% CI (1.51-10.89), mechanical ventilation (AHR:12, 95%CI (3-45), absence of thromboprophylaxis (AHR:10.8,95% CI (6.04-19.29), absence of enteral feeding (AHR:3.56, 95% CI (2.20-5.78) were variables associated with ICU-mortality among patients admitted to surgical intensive care unit.

Conclusions: The overall ICU-mortality of patients admitted to our surgical intensive care unit was higher compared to patients admitted to similar intensive care unit in developed countries. The variables associated to ICU-mortality among patients admitted to surgical intensive care unit were abnormal serum potassium level, lower GCS score, mechanical support, hypoxia, absence of thromboprophylaxis, and enteral feeding.

Keywords: Incidence; Intensive care unit; Mortality; Predictors; Surgical.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

The authors declares no conflict of interest in preparing this article.

Figures

Fig. 1
Fig. 1
STROBE diagram shows the study participants who were included and excluded in the study (STROBE: Strengthening the reporting of observational studies in epidemiology)
See this image and copyright information in PMC

References

    1. Adhikari NK, Fowler RA, Bhagwanjee S, Rubenfeld GD. Critical care and the global burden of critical illness in adults. The Lancet. 2010;376(9749):1339–46. - PMC - PubMed
    1. Dobson GP. Trauma of major surgery: a global problem that is not going away. Int J Surg (London England) 2020;81:47–54. - PMC - PubMed
    1. Weiser TG, Regenbogen SE, Thompson KD, Haynes AB, Lipsitz SR, Berry WR, Gawande AA. An estimation of the global volume of surgery: a modelling strategy based on available data. The Lancet. 2008;372(9633):139–44. - PubMed
    1. Bickler SW, Spiegel DA, Weiser TG, Regenbogen SE, Thompson KD. An estimation of the global volume of surgery: a modelling strategy based on available data. Commentary. Lancet (British edition) 2008, 372(9633). - PubMed
    1. Vincent J-L, Marshall JC, Ñamendys-Silva SA, François B, Martin-Loeches I, Lipman J, Reinhart K, Antonelli M, Pickkers P, Njimi H. Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit. The lancet Respiratory medicine. 2014;2(5):380–6. - PubMed

Publication types