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Review
. 2023 Aug 3:14:1218867.
doi: 10.3389/fphar.2023.1218867. eCollection 2023.

Cyclodextrin nanoparticles in targeted cancer theranostics

Roshnee Bose  1 , Maharsh Jayawant  1 , Rajesh Raut  2 , Jaya Lakkakula  1   3 , Arpita Roy  4 , Saad Alghamdi  5 , Naeem F Qusty  5 , Rohit Sharma  6 , Devvret Verma  7 , Mayeen Uddin Khandaker  8   9 , Abdullah Almujally  10 , Nissren Tamam  11 , Abdelmoneim Sulieman  12
Affiliations
Review

Cyclodextrin nanoparticles in targeted cancer theranostics

Roshnee Bose et al. Front Pharmacol. .

Abstract

The field of cancer nanotheranostics is rapidly evolving, with cyclodextrin (CD)-based nanoparticles emerging as a promising tool. CDs, serving as nanocarriers, have higher adaptability and demonstrate immense potential in delivering powerful anti-cancer drugs, leading to promising and specific therapeutic outcomes for combating various types of cancer. The unique characteristics of CDs, combined with innovative nanocomplex creation techniques such as encapsulation, enable the development of potential theranostic treatments. The review here focuses mainly on the different techniques administered for effective nanotheranostics applications of CD-associated complex compounds in the domain of cancer treatments. The experimentations on various loaded drugs and their complex conjugates with CDs prove effective in in vivo results. Various cancers can have potential nanotheranostics cures using CDs as nanoparticles along with a highly efficient process of nanocomplex development and a drug delivery system. In conclusion, nanotheranostics holds immense potential for targeted drug delivery and improved therapeutic outcomes, offering a promising avenue for revolutionizing cancer treatments through continuous research and innovative approaches.

Keywords: cancer; cyclodextrin; diagnosis; imaging; theranostics.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

None
Cyclodextrin (CD)-based nanotheranostics for cancer treatment.
FIGURE 1
FIGURE 1
Action of CD NPs in the treatment of breast cancer.
FIGURE 2
FIGURE 2
CD-based nanotheranostics for cervical cancer treatment.
FIGURE 3
FIGURE 3
Use of various CD NPs in the treatment and diagnostics of lung cancer.
FIGURE 4
FIGURE 4
CD-based NPs for liver cancer theranostics.
See this image and copyright information in PMC

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