Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Jun 2;4(2):e288.
doi: 10.1097/AS9.0000000000000288. eCollection 2023 Jun.

Comment on "Locoregional Failure During and After Short-Course Radiotherapy Followed by Chemotherapy and Surgery Compared to Long-Course Chemoradiotherapy and Surgery: A Five-Year Follow-Up of the RAPIDO Trial": The RAPIDO Trial Does Not Achieve Its Primary Endpoint

Affiliations
Comment

Comment on "Locoregional Failure During and After Short-Course Radiotherapy Followed by Chemotherapy and Surgery Compared to Long-Course Chemoradiotherapy and Surgery: A Five-Year Follow-Up of the RAPIDO Trial": The RAPIDO Trial Does Not Achieve Its Primary Endpoint

Olivier Riou et al. Ann Surg Open. .
No abstract available

PubMed Disclaimer

Comment on

References

    1. Dijkstra EA, Nilsson PJ, Hospers GAP, et al. . Locoregional failure during and after short-course radiotherapy followed by chemotherapy and surgery compared to long-course chemoradiotherapy and surgery—a five-year follow-up of the RAPIDO trial [published online ahead of print January 20, 2023]. Ann Surg. doi: 10.1097/SLA.0000000000005799. - PMC - PubMed
    1. Conroy T, Bosset J-F, Etienne P-L, et al. ; Unicancer Gastrointestinal Group and Partenariat de Recherche en Oncologie Digestive (PRODIGE) Group. Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 2021;22:702–715. - PubMed
    1. Brenner DJ, Hlatky LR, Hahnfeldt PJ, et al. . The linear-quadratic model and most other common radiobiological models result in similar predictions of time-dose relationships. Radiat Res. 1998;150:83–91. - PubMed
    1. Suwinski R, Wzietek I, Tarnawski R, et al. . Moderately low alpha/beta ratio for rectal cancer may best explain the outcome of three fractionation schedules of preoperative radiotherapy. Int J Radiat Oncol Biol Phys. 2007;69:793–799. - PubMed
    1. Glynne-Jones R, Hollingshead J. TNT and local recurrence in the RAPIDO trial—untangling the puzzle [published online ahead of print March 2, 2023]. Nat Rev Clin Oncol. doi: 10.1038/s41571-023-00751-4. - PubMed