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. 2023 Jun 22;4(3):867-868.
doi: 10.1002/jha2.706. eCollection 2023 Aug.

An ETV6::NTRK3 fusion transcript in a core-binding factor acute myeloid leukemia

Lucie Coster  1 , Françoise Huguet  2 , Alban Canali  1 , Jean-Baptiste Rieu  1 , Véronique Mansat- De Mas  1   3
Affiliations

An ETV6::NTRK3 fusion transcript in a core-binding factor acute myeloid leukemia

Lucie Coster et al. EJHaem. .
No abstract available

Keywords: acute myeloid leukemia; core‐binding factor leukemia; fusion transcript; translocation; tyrosine kinase inhibitor.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Blood smear showed blastic cells with irregular nuclei, dispersed chromatin and vacuolated cytoplasm suggestive of an acute myeloid leukemia of monocytic lineage (left panel, May Grünwald Giemsa stain, ×100 objective). A three‐way translocation t(6;21;8) was identified on the karyotype (yellow arrows) (right panel, G bands, Leishman stain, ×63 objective).
FIGURE 2
FIGURE 2
FISH showed a RUNX1::RUNX1T1 rearrangement (left panel, homemade RUNX1‐RUNX1T1 Texas Red—fluorescein probe, ×100 objective) and an ETV6 rearrangement (right panel, homemade ETV6 double color Texas Red—fluorescein probe, ×100 objective).
See this image and copyright information in PMC

References

    1. EJHaem. 2023 Jun 22;4(3):867-868 - PubMed