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Case Reports
. 2023 Jul 20;15(7):e42192.
doi: 10.7759/cureus.42192. eCollection 2023 Jul.

Adult-Onset Still's Disease (AOSD) Associated With Collagenous Colitis (CC) and Basedow's Disease: A Case Report

Alina Stiuliuc  1 , Abeline Kapuczinski  1 , Marjolaine Weynand  2 , Camille Lemoine  1 , Muhammad Soyfoo  1
Affiliations
Case Reports

Adult-Onset Still's Disease (AOSD) Associated With Collagenous Colitis (CC) and Basedow's Disease: A Case Report

Alina Stiuliuc et al. Cureus. .

Abstract

Adult-onset Still's disease (AOSD) is a rare auto-inflammatory syndrome of unknown etiology. Basedow's disease is a common cause of auto-immune hyperthyroidism. Collagenous colitis (CC) is a form of microscopic colitis (MC) affecting predominantly young women. While the etiology of the disease remains unclear, some studies suggest the role of auto-immunity. The association between AOSD and Basedow's disease has been reported in previous cases, suggesting auto-inflammation as a potential trigger of relapsing thyroid dysfunction. Although the co-existence of AOSD with inflammatory gastrointestinal disorders such as Crohn's disease and ulcerative colitis has also been described, we did not find any correlation with MC in the literature. We here describe the case of a woman having AOSD associated with Basedow's disease and CC.

Keywords: adult onset still's disease (aosd); basedow’s disease; collagenous colitis; inflammatory disease; thyroid orbitopathy.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Ferritin levels over time.
Figure 2
Figure 2. Splenomegaly on abdominal echography.
Figure 3
Figure 3. Summary of the patient's evolution over time.
See this image and copyright information in PMC

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