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Review
. 2023 Nov 1;34(6):470-475.
doi: 10.1097/ICU.0000000000000996. Epub 2023 Aug 21.

Neuro-ophthalmic complications of varicella-zoster virus

Toluwalase O Tofade  1 , Bart K Chwalisz  1   2
Affiliations
Review

Neuro-ophthalmic complications of varicella-zoster virus

Toluwalase O Tofade et al. Curr Opin Ophthalmol. .

Abstract

Purpose of review: This review broadly describes recent neuro-ophthalmic manifestations of varicella-zoster virus (VZV) reported in literature.

Recent findings: Despite varicella vaccination, the incidence of herpes zoster continues to rise, potentially leading to devastating consequences when ocular complications occur.A small but growing literature documents cases of retinal disease because of varicella reactivation after SARS-CoV-2 vaccination, ischemic optic neuropathy occurring during herpes zoster ophthalmicus, VZV-induced orbital apex syndrome, and immune-mediated ocular complications in patients with prior neuro-ophthalmic manifestations of VZV.

Summary: It is important for clinicians to keep abreast of the diverse neuro-ophthalmic manifestations of VZV as early diagnosis and treatment often lead to better visual outcomes.

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References

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    1. Edgerton AE. Herpes Zoster ophthalmicus: report of cases and a review of literature. Trans Am Ophthalmol Soc 1942; 40:390–439.

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