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Randomized Controlled Trial
. 2023 Jul-Aug;27(4):100531.
doi: 10.1016/j.bjpt.2023.100531. Epub 2023 Aug 11.

Effects of a foot-ankle muscle strengthening program on pain and function in individuals with knee osteoarthritis: a randomized controlled trial

Glauko A F Dantas  1 , Isabel C N Sacco  2 , Angélica V Ferrari  3 , Alessandra B Matias  2 , Ricky Watari  2 , Larissa V M Oliveira  3 , Thainá R Marcon  3 , José A Fatore  3 , Henrique Pott-Junior  4 , Tania F Salvini  3
Affiliations
Randomized Controlled Trial

Effects of a foot-ankle muscle strengthening program on pain and function in individuals with knee osteoarthritis: a randomized controlled trial

Glauko A F Dantas et al. Braz J Phys Ther. 2023 Jul-Aug.

Abstract

Background: Foot-ankle exercises could improve pain and function of individuals with KOA and need to be tested.

Objective: To investigate whether an 8-week foot-ankle muscle strengthening program is effective for individuals with KOA to reduce pain and improve function.

Methods: In this randomized controlled trial, individuals diagnosed with clinical and radiographic KOA were randomized into the intervention (supervised foot-ankle strengthening exercise program three times a week for 8 weeks) or control (usual care and recommendations of the healthcare team) group. Effectiveness was assessed by changes in clinical and functional outcomes between baseline and 8 weeks with pain as the primary outcome. ANCOVA tests using the intervention group as a reference and sex, body mass index, and baseline values as covariates assessed between-group differences.

Results: The intervention group showed lower pain scores (-4.4 units; 95%CI = -7.5, -1.1), better function (-7.1 units; 95%CI = -12.7, -1.4), higher total functional score (-11.9 units; 95%CI = -20.7, -3.1), with confidence intervals indicating a potential for the differences to be clinically meaningful, and better scores for the 30-s chair stand test (2.7 repetitions; 95%CI = 1.1, 4.1), with a confidence interval indicating a moderate clinically meaningful difference, compared to the controls.

Conclusion: The 8-week foot-ankle exercise program showed positive, and potentially clinically meaningful, effects on knee pain and physical function among individuals with KOA, when compared to usual care.

Trial registration: NCT04154059. https://clinicaltrials.gov/ct2/show/NCT04154059.

Keywords: Knee; Osteoarthritis; Physical-activity based intervention; Randomized controlled trial.

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Conflict of interest statement

Conflicts of interest None.

Figures

Fig 1
Fig. 1
Flow diagram of study.
See this image and copyright information in PMC

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