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Editorial
. 2023;30 Suppl 1(1):3-7.
doi: 10.1159/000533611. Epub 2023 Aug 21.

2nd European Psychoneuroimmunology Network Autumn School: The Skin-Brain Axis and the Breaking of Barriers

Eva Peters  1   2 , Adriana Del Rey  3 , Karsten Krüger  4 , Christoph Rummel  2   5
Affiliations
Editorial

2nd European Psychoneuroimmunology Network Autumn School: The Skin-Brain Axis and the Breaking of Barriers

Eva Peters et al. Neuroimmunomodulation. 2023.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1.
Fig. 1.
Interactions between the skin and the brain are bidirectional and enable adaptation to environmental change and organ remodeling requirements. Skin inflammation mechanisms are analog to inflammation at other borders between the organism and the environment and always involve the brain by the release of mediators such as neuroendocrine signaling molecules, namely neurotransmitters, neuropeptides, neurotrophins, hormones, and cytokines. The brain and skin also communicate through immune cell trafficking. Communication generates oxidative and metabolic stress, and in proinflammatory conditions, this interacts with mental health in the dimension mood and behavior. Lifestyle factors act as moderators and potential therapeutic tools in the interaction. The figure was created with BioRender.com.
See this image and copyright information in PMC

References

    1. Dhabhar FS. Effects of stress on immune function: the good, the bad, and the beautiful. Immunol Res. 2014;58(2–3):193–210. 10.1007/s12026-014-8517-0. - DOI - PubMed
    1. Pflieger FJ, Hernandez J, Schweighofer H, Herden C, Rosengarten B, Rummel C. The role of neutrophil granulocytes in immune-to-brain communication. Temperature. 2018;5(4):296–307. 10.1080/23328940.2018.1538598. - DOI - PMC - PubMed
    1. Weyh C, Kruger K, Strasser B. Physical activity and diet shape the immune system during aging. Nutrients. 2020;12(3):622. 10.3390/nu12030622. - DOI - PMC - PubMed
    1. Peters EMJ, Schedlowski M, Watzl C, Gimsa U. To stress or not to stress: brain-behavior-immune interaction may weaken or promote the immune response to SARS-CoV-2. Neurobiol Stress. 2021;14:100296. 10.1016/j.ynstr.2021.100296. - DOI - PMC - PubMed
    1. Passeron T, Zouboulis CC, Tan J, Andersen ML, Katta R, Lyu X, et al. . Adult skin acute stress responses to short-term environmental and internal aggression from exposome factors. J Eur Acad Dermatol Venereol. 2021;35(10):1963–75. 10.1111/jdv.17432. - DOI - PMC - PubMed

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