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. 2023 Aug 21;109(4):830-834.
doi: 10.4269/ajtmh.23-0176. Print 2023 Oct 4.

Perceptions Associated with Noncompliance to Community-Wide Mass Drug Administration for Soil-Transmitted Helminths

Kulandaipalayam Natarajan Sindhu  1 , Kumudha Aruldas  1 , Saravanakumar Puthupalayam Kaliappan  1 , Elavarasan Mahendran  1 , Judd L Walson  2   3   4   5   6 , Arianna Rubin Means  2   6 , Sitara Swarna Rao Ajjampur  1
Affiliations

Perceptions Associated with Noncompliance to Community-Wide Mass Drug Administration for Soil-Transmitted Helminths

Kulandaipalayam Natarajan Sindhu et al. Am J Trop Med Hyg. .

Abstract

Mass drug administration (MDA) is a key strategy for the control of soil-transmitted helminths (STHs). Within MDA programs, poor and non-random compliance threaten successful control of STHs. A case-control study was conducted comparing perceptions among non-compliant participants with compliant participants during a community-wide MDA (cMDA) with albendazole in southern India. Common reasons cited for non-compliance were that the individual was not infected with STH (97.4%), the perception that he/she was healthy (91%), fear of side-effects (12.8%), and dislike of consuming tablets (10.3%). Noncompliance was associated with poor awareness of intestinal worms (odds ratio [OR]: 9.63, 95% CI: 2.11-43.84), the perception that cMDA was only required for those with worms (OR: 2.14, 95% CI: 1.06-4.36), and the perception that the drug is not safe during pregnancy (OR: 2.19, 95% CI: 1.18-4.07) or when on concomitant medications (OR: 3.14, 95% CI: 1.38-7.15). Understanding of perceptions driving noncompliance can provide valuable insights to optimize participation during MDA for STHs.

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Figures

Figure 1.
Figure 1.
Flowchart depicting the selection of cases and controls from the community-wide mass drug administration (cMDA), round 3, for the noncompliance survey.
See this image and copyright information in PMC

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