Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec;12(4):635-642.
doi: 10.1007/s13668-023-00490-z. Epub 2023 Aug 22.

Narrative Review of Probiotic Use on the Recovery of Postoperative Patients with Esophageal Cancer

Affiliations
Review

Narrative Review of Probiotic Use on the Recovery of Postoperative Patients with Esophageal Cancer

Edzel Lorraine Co et al. Curr Nutr Rep. 2023 Dec.

Abstract

Purpose of review: This narrative review discusses the significance of probiotic therapy in the postoperative care of patients with esophageal cancer and its role as an adjunct therapy to other treatment modalities for esophageal cancer.

Recent findings: As such, there is an emerging need to address any malnutrition and gastrointestinal problems occurring in these patients which tend to have a strong negative impact on their prognosis. Probiotic effects on esophageal cancer biomarkers suggest that there is a positive correlation between these two factors. However, the beneficial effects remain controversial and warrant further investigation. Probiotics, now being widely utilized as postoperative therapy in some carcinomas of the gastrointestinal tract such as gastric cancer and colorectal cancer, have been shown in some clinical studies to positively impact the nutritional status of patients with esophageal cancer. Postoperative care among patients suffering from esophageal cancer is a very crucial aspect in the survival of these patients.

Keywords: Adjunct therapy; Esophageal cancer; Esophageal carcinoma; Gut microbiota; Postoperative recovery; Probiotics.

PubMed Disclaimer

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
    1. Schizas D, Lidoriki I, Moris D, Theodore Liakakos T. Nutritional management of esophageal cancer patients. In: Chai, J, editor. Esophageal Abnormalities. London: IntechOpen; 2017. Available from: https://www.intechopen.com/chapters/56177 , https://doi.org/10.5772/intechopen.69607 .
    1. Riccardi D, Allen K. Nutritional management of patients with esophageal and esophagogastric junction cancer. Cancer Control. 1999;6(1):64–72. https://doi.org/10.1177/107327489900600106 . - DOI - PubMed
    1. •• Liu C, Yang J, Dong W, Yuan J. Effects of probiotics on gastrointestinal complications and nutritional status of postoperative patients with esophageal cancer: a protocol of randomized controlled trial. Medicine (Baltimore). 2021;(11):100-e25138. https://doi.org/10.1097/MD.0000000000025138 . This article highlights the significance of probiotics in postoperative care of patients diagnosed with esophageal cancer.
    1. Tanaka K, Yano M, Motoori M, et al. Impact of perioperative administration of synbiotics in patients with esophageal cancer undergoing esophagectomy: a prospective randomized controlled trial. Surgery. 2012;152(5):832–42. https://doi.org/10.1016/j.surg.2012.02.021 . - DOI - PubMed
    1. Kanazawa H, Nagino M, Kamiya S, et al. Synbiotics reduce postoperative infectious complications: a randomized controlled trial in biliary cancer patients undergoing hepatectomy. Langenbecks Arch Surg. 2005;390(2):104–13. https://doi.org/10.1007/s00423-004-0536-1 . - DOI - PubMed

LinkOut - more resources