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Meta-Analysis
. 2023 Nov;48(10):998-1005.
doi: 10.1177/17531934231193336. Epub 2023 Aug 22.

Surgical site infection following surgery for hand trauma: a systematic review and meta-analysis

Justin C Wormald  1 , Alexander J Baldwin  2 , Hayat Nadama  3 , Abigail Shaw  4 , Ryckie G Wade  5 , Dani Prieto-Alhambra  6 , Jonathan A Cook  6 , Jeremy N Rodrigues  7 , Matthew L Costa  1
Affiliations
Meta-Analysis

Surgical site infection following surgery for hand trauma: a systematic review and meta-analysis

Justin C Wormald et al. J Hand Surg Eur Vol. 2023 Nov.

Abstract

Surgical site infection is the most common healthcare-associated infection. Surgical site infection after surgery for hand trauma is associated with increased antibiotic prescribing, re-operation, hospital readmission and delayed rehabilitation, and in severe cases may lead to amputation. As the risk of surgical site infection after surgery for hand trauma remains unclear, we performed a systematic review and meta-analysis of all primary studies of hand trauma surgery, including randomized controlled trials, cohort studies, case-control studies and case series. A total of 8836 abstracts were screened, and 201 full studies with 315,618 patients included. The meta-analysis showed a 10% risk of surgical site infection in randomized control trials, with an overall risk of 5% when all studies were included. These summary statistics can be used clinically for informed consent and shared decision making, and for power calculations for future clinical trials of antimicrobial interventions in hand trauma.

Keywords: Hand surgery; infection; systematic review; trauma.

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Conflict of interest statement

Declaration of conflicting interestsThe authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
PRISMA flow chart.
Figure 2.
Figure 2.
Risk of bias of included studies.
See this image and copyright information in PMC

References

    1. Ademuyiwa AO, Hardy P, Runigamugabo E, et al.. Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial. J Hand Surg Eur. 2021, 46: 1003–5. - PMC - PubMed
    1. Allegranzi B, Nejad SB, Combescure C, et al.. Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. J Hand Surg Eur. 2011, 36: 239–47. - PubMed
    1. Bachoura A, Guitton TG, Smith MR, Vrahas MS, Zurakowski D, Ring D. Infirmity and injury complexity are risk factors for surgical-site infection after operative fracture care. J Hand Surg Eur. 2011, 36: 105–11. - PMC - PubMed
    1. Baldwin AJ, Jackowski A, Jamal A, et al.. Risk of surgical site infection in hand trauma, and the impact of the SARS-CoV-2 pandemic: a cohort study. J Hand Surg Eur. 2021, 46: 623–30. - PMC - PubMed
    1. Constantine RS, Le ELH, Gehring MB, Ohmes L, Iorio ML. Risk factors for infection after distal radius fracture fixation: analysis of impact on cost of care. J Hand Surg Eur. 2022, 47: 62–9. - PMC - PubMed

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