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Editorial
. 2023 Dec;294(6):684-686.
doi: 10.1111/joim.13713. Epub 2023 Aug 22.

Even effective drugs require adequately powered trials: Systemic bevacizumab in hereditary hemorrhagic telangiectasia

Hanny Al-Samkari  1   2
Affiliations
Editorial

Even effective drugs require adequately powered trials: Systemic bevacizumab in hereditary hemorrhagic telangiectasia

Hanny Al-Samkari. J Intern Med. 2023 Dec.
No abstract available

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Conflict of interest statement

Conflicts of interest:

H. Al-Samkari (universal disclosures): Research funding to institution (Agios, Sobi, Novartis, Vaderis, Amgen) and consultancy (Agios, Sobi, Moderna, Novartis, Rigel, argenx, Forma, Pharmacosmos).

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References

    1. Dupuis-Girod S, Riviere S, Lavigne C, et al. Efficacy and safety of intravenous bevacizumab on severe bleeding associated with hereditary hemorrhagic telangiectasia: A national, randomized multicenter trial. J Intern Med 2023. - PubMed
    1. Al-Samkari H. Giving hereditary haemorrhagic telangiectasia the attention it deserves. The Lancet Haematology 2021; 8: e472–e4. - PubMed
    1. Al-Samkari H. Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care. Blood 2021; 137: 888–95. - PubMed
    1. Al-Samkari H, Kritharis A, Rodriguez-Lopez JM, Kuter DJ. Systemic bevacizumab for the treatment of chronic bleeding in hereditary haemorrhagic telangiectasia. J Intern Med 2019; 285: 223–31. - PubMed
    1. Al-Samkari H. Systemic Antiangiogenic Therapies for Bleeding in Hereditary Hemorrhagic Telangiectasia: A Practical, Evidence-Based Guide for Clinicians. Semin Thromb Hemost 2022; 48: 514–28. - PubMed

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