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Comparative Study
. 1986 Sep;49(9):1050-4.
doi: 10.1136/jnnp.49.9.1050.

A pharmacodynamic evaluation of midazolam as an antiepileptic compound

S Jawad, J Oxley, J Wilson, A Richens
Comparative Study

A pharmacodynamic evaluation of midazolam as an antiepileptic compound

S Jawad et al. J Neurol Neurosurg Psychiatry. 1986 Sep.

Abstract

Midazolam is a water soluble 1,4 benzodiazepine which is suitable for intramuscular administration. It is currently used for pre-medication and the induction of anaesthesia. Its antiepileptic properties have been evaluated by studying its effect on interictal spikes on the EEG of six adult epileptic patients. The results indicate that intramuscular midazolam 15 mg is more effective than intramuscular diazepam 10 mg in abolishing interictal spikes and as effective as intravenous diazepam 20 mg five minutes after administration.

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References

    1. Anesth Analg. 1978 Jan-Feb;57(1):1-5 - PubMed
    1. Br J Clin Pharmacol. 1981 May;11(5):443-56 - PubMed
    1. Epilepsia. 1982 Jun;23(3):323-31 - PubMed
    1. Br J Clin Pharmacol. 1983 Sep;16(3):285-9 - PubMed
    1. Br J Clin Pharmacol. 1983;16 Suppl 1:17S-27S - PubMed

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