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Case Reports
. 2023 Aug 23;17(8):e01700.
doi: 10.1213/XAA.0000000000001700. eCollection 2023 Aug 1.

Propofol Induced Subacute Cutaneous Lupus Erythematosus: A Case Report

Joseph A Schoenfeldt  1 , Michael A Howard  1 , Deeba Masood  1 , Daniel S Cormican  2
Affiliations
Case Reports

Propofol Induced Subacute Cutaneous Lupus Erythematosus: A Case Report

Joseph A Schoenfeldt et al. A A Pract. .

Abstract

We report a case of a woman who experienced unexplained recurrent rashes of varying severity after multiple exposures to anesthesia, and then 2 successful surgeries under general anesthesia with no resultant rashes after removing propofol from her anesthetic plans. We infer her previous postanesthetic rashes were likely associated with drug-induced subacute cutaneous lupus erythematosus (DI-SCLE) triggered by propofol.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1.
Figure 1.
Painful rash present after previous surgery.
Figure 2.
Figure 2.
Painful rash present after previous surgery.
Figure 3.
Figure 3.
Painful rash present after previous surgery.
See this image and copyright information in PMC

References

    1. Folino TB, Muco E, Safadi AO, et al. . Propofol. National Center for Biotechnology Information. Published May 8, 2022. Accessed July 6, 2022. Available at: https://pubmed.ncbi.nlm.nih.gov/28613634/.
    1. DIPRIVAN (propofol) injectable emulsion, USP—Food and Drug Administration. Published April 2017. Accessed March 2, 2022. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019627s066lbl.pdf.
    1. Yu Y, Gui H, Xiong K, Fang X, He J. Progression of systemic lupus erythematosus associated with propofol administration: a case report. Eur J Hosp Pharm. 2018;25:225–227. - PMC - PubMed
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